Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. Article › Research › Not peer-reviewed
  2. Published

    Comparison of intestinal and hepatic sulphation and glucuronidation for a range of drugs

    Cubitt, H., Houston, JB. & Galetin, A., 2009, In : Drug Metabolism Reviews. 41 (Suppl. 1)

    Research output: Contribution to journalArticle

  3. Published

    Prediction of the intestinal availability and associated inter-individual variability for drugs with high intestinal first-pass metabolism

    Gertz, M., Harrison, A., Davis, J., Houston, JB. & Galetin, A., 2009, In : Drug Metabolism Reviews. 41 (Suppl. 1): 50

    Research output: Contribution to journalArticle

  4. Article › Research › Peer-reviewed
  5. Published

    A comprehensive assessment of repaglinide metabolic pathways: Impact of choice of in vitro system and relative enzyme contribution to in vitro clearance

    Säll, C., Houston, J. B. & Galetin, A., Jul 2012, In : Drug Metabolism and Disposition. 40, 7, p. 1279-1289 10 p.

    Research output: Contribution to journalArticle

  6. Published

    A pragmatic randomized controlled trial of thiopurine methyltransferase genotyping prior to azathioprine treatment: The TARGET study

    Newman, W. G., Payne, K., Tricker, K., Roberts, S. A., Fargher, E., Pushpakom, S., Alder, J. E., Sidgwick, G. P., Payne, D., Elliott, R. A., Heise, M., Elles, R., Ramsden, S. C., Andrews, J., Houston, J. B., Qasim, F., Shaffer, J., Griffiths, C. E. M., Ray, D. W., Bruce, I. & 1 others, Ollier, W. E. R., Jun 2011, In : Pharmacogenomics. 12, 6, p. 815-826 11 p.

    Research output: Contribution to journalArticle

  7. Published

    Absorption of prednisolone in patients with Crohn's disease

    Shaffer, J. A., Williams, S. E., Turnberg, L. A., Houston, J. & Rowland, M., Mar 1983, In : Gut. 24, 3, p. 182-6 5 p.

    Research output: Contribution to journalArticle

  8. Published

    An integrated approach to the prediction of systemic toxicity using computer-based biokinetic models and biological in vitro test methods: Overview of a prevalidation study based on the ECITTS project

    Dejongh, J., Forsby, A., Houston, J. B., Beckman, M., Combes, R. & Blaauboer, B. J., Aug 1999, In : Toxicology in Vitro. 13, 4-5, p. 549-554 5 p.

    Research output: Contribution to journalArticle

  9. Published

    Application of a physiologically based pharmacokinetic model to assess propofol hepatic and renal glucuronidation in isolation: Utility of in vitro and in vivo data

    Gill, K. L., Gertz, M., Houston, J. B. & Galetin, A., Apr 2013, In : Drug Metabolism and Disposition. 41, 4, p. 744-753 9 p.

    Research output: Contribution to journalArticle

  10. Published

    Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: Comparison of dynamic and static models

    Guest, E. J., Rowland-Yeo, K., Rostami-Hodjegan, A., Tucker, G. T., Houston, J. B. & Galetin, A., Jan 2011, In : British Journal of Clinical Pharmacology. 71, 1, p. 72-87 15 p.

    Research output: Contribution to journalArticle

  11. Published

    Binding of drugs to hepatic microsomes: Comment and assessment of current prediction methodology with recommendation for improvement [1]

    Hallifax, D. & Houston, J. B., Apr 2006, In : Drug Metabolism and Disposition. 34, 4, p. 724-726 2 p.

    Research output: Contribution to journalArticle

  12. Published
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