Prof James HoustonBSc, PhD, DSc

Emeritus Professor

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Publications

  1. Published

    Comparison of clearance for three benzodiazepines determined by metabolite formation and substrate depletion methods in rat hepatic microsomes.

    Ahmed, S. & Houston, B., 2000, Drug Metabolism Reviews. Vol. 32, Suppl. 1.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  2. Published

    Sigmoidal kinetics in rat hepatic microsomes: studies with dextromethorphan, alprazolam and triazolam.

    Ahmed, S. & Houston, B., 1999, Proceeding of 7th Stowe School Symposium on Drug Metabolism.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  3. Published

    Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells

    Andrews, J., Abd-Ellah, M. F., Randolph, N. L., Kenworthy, K. E., Carlile, D. J., Friedberg, T. & Houston, J. B., 1 Nov 2002, In : Xenobiotica. 32, 11, p. 937-947 10 p.

    Research output: Contribution to journalArticle

  4. Published

    Pharmacogencomics and predictive drug metabolism

    Andrews, J., Pasksaleva, E., Galetin, A. & Houston, B., 2003, Pharmacogencomics and predictive drug metabolism. Pharmacogenomics Workshop, Annual Human Genome Meeting, Cancun, Mexico.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  5. Published

    In Silico Prediction of Hepatocellular Drug Binding

    Assmus, F., Houston, B. & Galetin, A., Jun 2015, host publication. Vol. A10.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  6. Published

    Incorporation of lysosomal sequestration in the mechanistic model for prediction of tissue distribution of basic drugs

    Assmus, F., Houston, J. & Galetin, A., 2017, In : European Journal of Pharmaceutical Sciences.

    Research output: Contribution to journalArticle

  7. Published

    Methodology for development of a physiological model incorporating CYP3A and P-glycoprotein for the prediction of intestinal drug absorption

    Badhan, R., Penny, J., Galetin, A. & Houston, J. B., Jun 2009, In : Journal of Pharmaceutical Sciences. 98, 6, p. 2180-2197 17 p.

    Research output: Contribution to journalArticle

  8. Published

    Scaling factors for the extrapolation of in vivo metabolic drug clearance from in vitro data: Reaching a consensus on values of human microsomal protein and hepatocellularity per gram of liver

    Barter, Z. E., Bayliss, M. K., Beaune, P. H., Boobis, A. R., Carlile, D. J., Edwards, R. J., Houston, J. B., Lake, B. G., Lipscomb, J. C., Pelkonen, O. R., Tucker, G. T. & Rostami-Hodjegan, A., Jan 2007, In : Current Drug Metabolism. 8, 1, p. 33-45 12 p.

    Research output: Contribution to journalArticle

  9. Published

    Prediction of drug kinetic properties:diazepam in human liver microsomes versus cDNA expressed CYP3A4 and 2C19.

    Bicknell, H. A., Worboys, P. D., Evans, D. & Houston, B., 1999, Proceeding of 7th Stowe School Symposium on Drug Metabolism.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  10. Published

    Regioselective and stereoselective hydroxylations of warfarin in human liver microsomes and cDNA expressed cytochrome P450.

    Bicknell, H. A., Worboys, P. D. & Houston, B., 2000, Drug Metabolism Reviews. Vol. 32, Suppl. 1.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

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