Prof Jacky SmithMB, ChB, FRCP, PhD

Chair (Teaching & Research)

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Research interests

Research interests include:

  • Measurement of cough and the cough reflex
  • Airway Innervation and mechanisms of neuronal sensitisation
  • Clinical trials of novel anti-tussive agents
  • The role of gastro-oesophageal reflux in chronic cough

Methodological knowledge

Clinical research skills: bronchial challenge testing, cough reflex sensitivity testing, pulmonary function testing, exhaled nitric oxide measurement, sputum induction, endo-bronchial biopsy, brushing and lavage, optico-electronic plethysmography, intra-oesophageal and gastric balloon pressure measurements

Clinical trials experience: design, applying for ethical approval, patient recruitment, data collection and analysis, including clinical trials of investigational medicinal products for the treatment of cough.

Statistics and data analysis skills: I have an interest in advanced statistical techniques such as factor analysis, cluster analysis and recently structural equation modelling.

Signal Processing Skills: I have a basic understanding of acoustic signal processing and speech recognition techniques from a close collaboration with computer scientists and engineers

Projects

Research and projects