Dr Jack Green

Research Associate (Neuroinflammation)

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Publications

  1. 2022
  2. Accepted/In press

    Looking into the IL-1 of the storm: Are inflammasomes the link between immunothrombosis and hyperinflammation in cytokine storm syndromes?

    Gleeson, T., Nordling, E., Kaiser, C., Lawrence, C. B., Brough, D., Green, J. & Allan, S., 24 Aug 2022, (Accepted/In press) In: Discovery Immunology.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages

    Hoyle, C., Green, J., Allan, S. & Brough, D., 1 Apr 2022, In: Immunology. 165, 4

    Research output: Contribution to journalArticlepeer-review

  4. Published

    LRRC8A is dispensable for a variety of microglial functions and response to acute stroke

    Cook, J. R., Gray, A. L., Lemarchand, E., Schiessl, I., Green, J. P., Newland, M. C., Dyer, D. P., Brough, D. & Lawrence, C. B., 12 Feb 2022, In: GLIA.

    Research output: Contribution to journalArticlepeer-review

  5. 2021
  6. Published

    NLRP3 activation in response to disrupted endocytic traffic

    Lee, B., Hoyle, C., Green, J., Wellens, R., Martín-Sánchez, F., Williams, D., Seoane Denicola, P., Bennett, H., Adamson, A., Lopez-Castejon, G., Lowe, M. & Brough, D., 16 Sep 2021, In: bioRxiv.

    Research output: Contribution to journalArticle

  7. 2020
  8. Accepted/In press

    Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation

    Lawrence, C. B., Rivers-Auty, J., Tapia Olivares, V., White, C., Daniels, M., Drinkall, S., Kennedy, P., Spence, H., Yu Shi, A., Green, J., Hoyle, C., Cook, J., Bradley, A., Mather, A., Peters, R., Tzeng, T-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 4 Dec 2020, (Accepted/In press) In: Journal of Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

    Green, J., Swanton, T., Morris, L., El-Sharkawy, L., Cook, J., Yu Shi, A., Beswick, J., Adamson, A., Humphreys, N., Bryce, R., Freeman, S., Lawrence, C. B. & Brough, D., 20 Nov 2020, In: eLife. 2020, 9, e59704.

    Research output: Contribution to journalArticlepeer-review

  10. E-pub ahead of print

    Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification

    Yu Shi, A., Green, J., Wellens, R., Lopez-Castejon, G. & Brough, D., 3 Nov 2020, (E-pub ahead of print) In: The FEBS Journal.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl- channel modulation

    Swanton, T., Beswick, J., Hammadi, H., Morris, L., Williams, D., De Cesco, S., El-sharkawy, L., Yu, S., Green, J., Davis, J., Lawrence, C., Brough, D. & Freeman, S., 12 Oct 2020, In: Chemical Science. 11, 43, p. 11720-11728 9 p.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Inhibition of the NLRP3 inflammasome by HSP90 inhibitors

    Nizami, S., Arunasalam, K., Green, J., Cook, J., Lawrence, C. B., Zarganes-Tzitzikas, T., Davis, J. B., Daniel, E. D. & Brough, D., 20 Sep 2020, In: Immunology.

    Research output: Contribution to journalArticlepeer-review

  13. Accepted/In press

    Mechanisms of NLRP3 Priming in Inflammaging and Age Related Diseases

    Gritsenko, A., Green, J., Brough, D. & Lopez-Castejon, G., 20 Aug 2020, (Accepted/In press) In: Cytokine and growth factor reviews.

    Research output: Contribution to journalArticlepeer-review

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Research output: Contribution to journalArticlepeer-review