Dr Hui Guo

Senior Lecturer in Biostatistics

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Publications

  1. 2019
  2. Published

    Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics

    Rowland, J., Akbarov, A., Eales, J., Xu, X., Dormer, J., Guo, H., Denniff, M., Jiang, X., Ranjzad, P., Nazgiewicz, A., Ribeiro Prestes, P., Antczak, A., Szulinska, M., Wise, I., Zukowska-Szczechowska, E., Bogdanski, P., Woolf, A. S., Samani, N. J., Charchar, F. J. & Tomaszewski, M., Mar 2019, In : Kidney International. 95, 3, p. 624-635 12 p.

    Research output: Contribution to journalArticle

  3. Published

    Sensitivity to Pain Expectations: A Bayesian Model of Individual Differences

    Hoskin, R., Berzuini, C., Acosta-Kane, D., El Deredy, W., Guo, H. & Talmi, D., Jan 2019, In : Cognition.

    Research output: Contribution to journalArticle

  4. Published

    Long-term survival following on-pump and off-pump coronary artery bypass graft: a propensity score-matched analysis

    Kirmani, B. H., Guo, H., Ahmadyur, O. & Bittar, M. N., 2019, In : European Journal of Cardio-Thoracic Surgery.

    Research output: Contribution to journalArticle

  5. 2018
  6. Published

    Mendelian randomisation analysis of clustered causal effects of body mass on cardiometabolic biomarkers

    Conde, S., Xu, X., Guo, H., Perola, M., Fazia, T., Bernardinelli, L. & Berzuini, C., 9 Jul 2018, In : BMC Bioinformatics. 19, S7

    Research output: Contribution to journalArticle

  7. Published

    A Bayesian approach to Mendelian randomisation with multiple pleiotropic variants

    Berzuini, C., Guo, H., Burgess, S. & Bernardinelli, L., 2018, In : Biostatistics.

    Research output: Contribution to journalArticle

  8. Published

    Molecular insights into genome-wide association studies of chronic kidney disease-defining traits

    Xu, X., Eales, J., Akbarov, A., Guo, H., Becker, L., Talavera, D., Ashraf, F., Nawaz, J., Pramanik, S., Bowes, J., Jiang, X., Dormer, J., Denniff, M., Antczak, A., Sszulinska, M., Wise, I., Prestes, P. R., Glyda, M., Bogdanski, P., Zukowska-Szczechowska, E. & 5 others, Berzuini, C., Woolf, A. S., Samani, N., Charchar, F. J. & Tomaszewski, M., 2018, In : Nature Communications. 9

    Research output: Contribution to journalArticle

  9. 2017
  10. Published

    Investigating Multiple Sclerosis genetic susceptibility on the founder population of east-central Sardinia via association and linkage analysis of immune-related loci

    Fazia, T., Pastorino, R., Foco, L., Han, L., Abney, M., Beecham, A., Hadjixenofontos, A., Guo, H., Gentilini, D., Papachristou, C., Bitti, P. P., Ticca, A., Berzuini, C., McCauley, J. & Bernardinelli, L., 2017, In : Multiple Sclerosis Journal.

    Research output: Contribution to journalArticle

  11. 2016
  12. Published

    Sufficient covariate, propensity variable and doubly robust estimation

    Guo, H., Dawid, AP. & Berzuini, G., 2016, Statistical Causal Inferences and Their Applications in Public Health Research. He, H., Wu, P. & Chen, D-G. D. (eds.). Springer Nature, p. 49-89

    Research output: Chapter in Book/Report/Conference proceedingChapter

  13. 2015
  14. Published

    Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes

    Cooper, N. J., Shtir, C. J., Smyth, D. J., Guo, H., Swafford, A. D., Zanda, M., Hurles, M. E., Walker, N. M., Plagnol, V., Cooper, J. D., Howson, J. M. M., Burren, O. S., Onengut-Gumuscu, S., Rich, S. S. & Todd, J. A., 2015, In : Human Molecular Genetics. 24, 6, p. 1774-1790 16 p.

    Research output: Contribution to journalArticle

  15. Published

    Dissection of a complex disease susceptibility region using a Bayesian stochastic search approach to fine mapping

    Wallace, C., Cutler, AJ., Pontikos, N., Pekalski, ML., Burren, OS., Cooper, JD., Garcia, AR., Ferreira, RC., Guo, H., Walker, NM., Smyth, DJ., Rich, SS., Onengut-Gumuscu, S., Sawcer, SJ., Ban, M., Richardson, S., Todd, JA. & Wicker, LS., 2015, In : P L o S Genetics (Online).

    Research output: Contribution to journalArticle

  16. Published

    Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

    Onengut-Gumuscu, S., Chen, W-M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., Farber, E., Bonnie, J. K., Szpak, M., Schofield, E., Achuthan, P., Guo, H., Fortune, M. D., Stevens, H., Walker, N. M., Ward, L. D., Kundaje, A., Kellis, M., Daly, M. J., Barrett, J. C. & 7 others, Cooper, J. D., Deloukas, P., Type I Diabetes Genetics Consortium, Todd, J. A., Wallace, C., Concannon, P. & Rich, S. S., 2015, In : Nature Genetics. 47, p. 381-386 5 p.

    Research output: Contribution to journalArticle

  17. Published

    Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases

    Guo, H., Fortune, MD., Burren, OS., Schofield, E., Todd, JA. & Wallace, C., 2015, In : Human Molecular Genetics. 24, 12, p. 3305-3313 8 p.

    Research output: Contribution to journalArticle

  18. Published

    Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

    Fortune, MD., Guo, H., Burren, O., Schofield, E., Walker, NM., Ban, M., Sawcer, SJ., Bowes, J., Worthington, J., Barton, A., Eyre, S., Todd, JA. & Wallace, C., 2015, In : Nature Genetics. 47, 7

    Research output: Contribution to journalArticle

  19. Published

    Widespread seasonal gene expression reveals annual differences in human immunity

    Castro-Dopico, X., Evangelou, E., Ferreira, RC., Guo, H., Pekalski, ML., Smyth, DJ., Cooper, N., Burren, OS., Fulford, AJ., Hennig, BJ., Prentice, A., Ziegler, AG., Bonifacio, E., Wallace, C. & Todd, JA., 2015, In : Nature Communications.

    Research output: Contribution to journalArticle

  20. 2014
  21. Published

    A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

    Pontikos, N., Smyth, D. J., Schuilenburg, H., Howson, J. M. M., Walker, N. M., Burren, O. S., Guo, H., Onengut-Gumuscu, S., Chen, W. M., Concannon, P., Rich, S. S., Jayaraman, J., Jiang, W., Traherne, J. A., Trowsdale, J., Todd, J. A. & Wallace, C., 11 Apr 2014, In : BMC Genomics. 15, 1, 274.

    Research output: Contribution to journalArticle

  22. Published

    A method for gene-based pathway analysis using genomewide association study summary statistics reveals new type 1 diabetes associations in ITGB7, FYN and ITGB1

    Evangelou, M., Smyth, DJ., Fortune, MD., Burren, OS., Walker, NM., Guo, H., Onengut-Gumuscu, S., Chen, WM., Concannon, P., Rich, SS., Todd, JA. & Wallace, C., 2014, In : Genetic Epidemiology. 38, 8, p. 661-670 9 p.

    Research output: Contribution to journalArticle

  23. Published

    A type I Interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes

    Ferreira, R. C., Guo, H., Coulson, R. M. R., Smyth, D. J., Pekalski, M. L., Burren, O. S., Cutler, A. J., Doecke, J. D., Flint, S., McKinney, E. F., Lyons, P. A., Smith, K. G. C., Achenbach, P., Beyerlein, A., Dunger, D. B., Clayton, D. G., Wicker, L. S., Todd, J. A., Bonifacio, E., Wallace, C. & 1 others, Ziegler, A. G., 2014, In : Diabetes. 63, 7, p. 2538-2550 12 p.

    Research output: Contribution to journalArticle

  24. Published

    Evaluation of whole brain health in aging and Alzheimer's disease: a standard procedure for scoring an MRI-based brain atrophy and lesion index.

    Guo, H., Song, X., Schmidt, M. H., Vandorpe, R., Yang, Z., LeBlanc, E., Zhang, J., Beyea, S., Zhang, Y. & Rockwood, K., 2014, In : Journal of Alzheimer's disease : JAD. 42, 2

    Research output: Contribution to journalArticle

  25. Published

    Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes

    Thompson, W. S., Pekalski, M. L., Simons, H. Z., Smyth, D. J., Castro-Dopico, X., Guo, H., Guy, C., Dunger, D. B., Arif, S., Peakman, M., Wallace, C., Wicker, L. S., Todd, J. A. & Ferreira, R. C., 2014, In : Clinical and experimental immunology. 177, 3, p. 571-585 14 p.

    Research output: Contribution to journalArticle

  26. Published
  27. 2013
  28. Published

    Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors

    Pekalski, M. L., Ferreira, R. C., Coulson, R. M. R., Cutler, A. J., Guo, H., Smyth, D. J., Downes, K., Dendrou, C. A., Dopico, X. C., Esposito, L., Coleman, G., Stevens, H. E., Nutland, S., Walker, N. M., Guy, C., Dunger, D. B., Wallace, C., Tree, T. I. M., Todd, J. A. & Wicker, L. S., 15 Mar 2013, In : Journal of Immunology. 190, 6, p. 2554-2566 12 p.

    Research output: Contribution to journalArticle

  29. 2012
  30. Published

    Seven newly identified loci for autoimmune thyroid disease

    Cooper, J. D., Simmonds, M. J., Walker, N. M., Burren, O., Brand, O. J., Guo, H., Wallace, C., Stevens, H., Coleman, G., Franklyn, J. A., Todd, J. A. & Gough, S. C. L., Dec 2012, In : Human Molecular Genetics. 21, 23, p. 5202-5208 6 p., dds357.

    Research output: Contribution to journalArticle

  31. 2010
  32. Published

    Sufficient covariates and linear propensity analysis

    Guo, H. & Dawid, A. P., 2010, Journal of Machine Learning Research|J. Mach. Learn. Res.. Journal of Machine Learning Research Workshop and Conference Proceedings, Vol. 9. p. 281-288 7 p.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution