Dr Hui Guo

Senior Lecturer in Biostatistics

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Publications

  1. 2015
  2. Published

    Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

    Onengut-Gumuscu, S., Chen, W-M., Burren, O., Cooper, N. J., Quinlan, A. R., Mychaleckyj, J. C., Farber, E., Bonnie, J. K., Szpak, M., Schofield, E., Achuthan, P., Guo, H., Fortune, M. D., Stevens, H., Walker, N. M., Ward, L. D., Kundaje, A., Kellis, M., Daly, M. J., Barrett, J. C. & 7 others, Cooper, J. D., Deloukas, P., Type I Diabetes Genetics Consortium, Todd, J. A., Wallace, C., Concannon, P. & Rich, S. S., 2015, In : Nature Genetics. 47, p. 381-386 5 p.

    Research output: Contribution to journalArticle

  3. Published

    Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases

    Guo, H., Fortune, MD., Burren, OS., Schofield, E., Todd, JA. & Wallace, C., 2015, In : Human Molecular Genetics. 24, 12, p. 3305-3313 8 p.

    Research output: Contribution to journalArticle

  4. Published

    Statistical Colocalization of Genetic Risk Variants for Related Autoimmune Diseases in the Context of Common Controls

    Fortune, MD., Guo, H., Burren, O., Schofield, E., Walker, NM., Ban, M., Sawcer, SJ., Bowes, J., Worthington, J., Barton, A., Eyre, S., Todd, JA. & Wallace, C., 2015, In : Nature Genetics. 47, 7

    Research output: Contribution to journalArticle

  5. Published

    Widespread seasonal gene expression reveals annual differences in human immunity

    Castro-Dopico, X., Evangelou, E., Ferreira, RC., Guo, H., Pekalski, ML., Smyth, DJ., Cooper, N., Burren, OS., Fulford, AJ., Hennig, BJ., Prentice, A., Ziegler, AG., Bonifacio, E., Wallace, C. & Todd, JA., 2015, In : Nature Communications.

    Research output: Contribution to journalArticle

  6. 2014
  7. Published

    A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples

    Pontikos, N., Smyth, D. J., Schuilenburg, H., Howson, J. M. M., Walker, N. M., Burren, O. S., Guo, H., Onengut-Gumuscu, S., Chen, W. M., Concannon, P., Rich, S. S., Jayaraman, J., Jiang, W., Traherne, J. A., Trowsdale, J., Todd, J. A. & Wallace, C., 11 Apr 2014, In : BMC Genomics. 15, 1, 274.

    Research output: Contribution to journalArticle

  8. Published

    A method for gene-based pathway analysis using genomewide association study summary statistics reveals new type 1 diabetes associations in ITGB7, FYN and ITGB1

    Evangelou, M., Smyth, DJ., Fortune, MD., Burren, OS., Walker, NM., Guo, H., Onengut-Gumuscu, S., Chen, WM., Concannon, P., Rich, SS., Todd, JA. & Wallace, C., 2014, In : Genetic Epidemiology. 38, 8, p. 661-670 9 p.

    Research output: Contribution to journalArticle

  9. Published

    A type I Interferon transcriptional signature precedes autoimmunity in children genetically at risk for type 1 diabetes

    Ferreira, R. C., Guo, H., Coulson, R. M. R., Smyth, D. J., Pekalski, M. L., Burren, O. S., Cutler, A. J., Doecke, J. D., Flint, S., McKinney, E. F., Lyons, P. A., Smith, K. G. C., Achenbach, P., Beyerlein, A., Dunger, D. B., Clayton, D. G., Wicker, L. S., Todd, J. A., Bonifacio, E., Wallace, C. & 1 others, Ziegler, A. G., 2014, In : Diabetes. 63, 7, p. 2538-2550 12 p.

    Research output: Contribution to journalArticle

  10. Published

    Evaluation of whole brain health in aging and Alzheimer's disease: a standard procedure for scoring an MRI-based brain atrophy and lesion index.

    Guo, H., Song, X., Schmidt, M. H., Vandorpe, R., Yang, Z., LeBlanc, E., Zhang, J., Beyea, S., Zhang, Y. & Rockwood, K., 2014, In : Journal of Alzheimer's disease : JAD. 42, 2

    Research output: Contribution to journalArticle

  11. Published

    Multi-parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes

    Thompson, W. S., Pekalski, M. L., Simons, H. Z., Smyth, D. J., Castro-Dopico, X., Guo, H., Guy, C., Dunger, D. B., Arif, S., Peakman, M., Wallace, C., Wicker, L. S., Todd, J. A. & Ferreira, R. C., 2014, In : Clinical and experimental immunology. 177, 3, p. 571-585 14 p.

    Research output: Contribution to journalArticle

  12. Published