Prof Hector ChinoyPhD FRCP BMBS MSc BMedSci

Professor of Rheumatology and Neuromuscular Disease HEFCE

View graph of relations

Research interests

My current research interest is in the immunogenetics of idiopathic inflammatory myopathy (IIM).

Objectives:

  • Further analysis of GWAS and Immunochip data generated from a UK-based and international cohort of IIM patients.
  • To facilitate and oversee replication association studies of disease susceptibility signals from GWAS and pan-autoimmune loci
  • To facilitate and oversee the identification of potential disease-causal variants within IIM susceptibility genes via genetic re-sequencing and high-throughput genotyping.
  • Coordinating a prospective collection of IIM data in the UK (MYOPROSP)
  • NHS England registry collection of IIM patients commencing rituximab (MYOACT)
  • Novel imaging modalities in IIM
  • Use of PROMS to measure disease activity in IIM
  • Dissemination of Euromyositis, a European-wide standardised web-based IIM database facility (collaboration)
  • To study subclinical atherosclerosis and endothelial dysfunction in IIM
  • To facilitate collection of blood and tissue as part of a muscle biobank and UKMYONET, a nationwide UK Clinical Research Network IIM study
  • To investigate the interaction of smoking and HLA-DRB1*03 for the development of myositis antibodies in IIM (collaboration)
  • To assist in the clinical and genetic phenotypic characterisation of IIM cases with novel autoantibody profiles (collaboration)
  • Management of idiopathic inflammatory myopathies: adult patients and professional specialists’ perspectives on current care in the UK (collaboration)

Projects

Research and projects

  1. MMRG: Manchester Myositis Research Group

    Chinoy, H., Lamb, J., Ollier, W., Rothwell, S., Lilleker, J., Oldroyd, A., Snedden, A., Platt, H. & New, P.

    1/01/10 → …

    Project: Research