Dr Gloria Lopez-Castejon BSc, PhD

Research Fellow

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Publications

  1. 2020
  2. E-pub ahead of print

    Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification

    Yu Shi, A., Green, J., Wellens, R., Lopez-Castejon, G. & Brough, D., 3 Nov 2020, (E-pub ahead of print) In: The FEBS Journal.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Priming is dispensable for NLRP3 inflammasome activation in human monocytes in vitro

    Gritsenko, A., Yu, S., Martín-Sánchez, F., Díaz Del Olmo, I., Nichols, E-M., Davis, D. M., Brough, D. & Lopez-Castejon, G., 30 Sep 2020, In: Frontiers in Immunology. 11, 565924.

    Research output: Contribution to journalArticlepeer-review

  4. Accepted/In press

    The NLRP3 inflammasome as a sensor of organelle dysfunction

    Seoane Denicola, P., Lee, B., Hoyle, C., Yu Shi, A., Lopez-Castejon, G., Lowe, M. & Brough, D., 18 Sep 2020, (Accepted/In press) In: Journal of Cell Biology.

    Research output: Contribution to journalArticlepeer-review

  5. Accepted/In press

    Mechanisms of NLRP3 Priming in Inflammaging and Age Related Diseases

    Gritsenko, A., Green, J., Brough, D. & Lopez-Castejon, G., 20 Aug 2020, (Accepted/In press) In: Cytokine and growth factor reviews.

    Research output: Contribution to journalArticlepeer-review

  6. 2019
  7. Published

    Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

    Gurumurthy, C. B., O’brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S. K., Beauchamp, M., Becker, K. A., Bernas, G., Brough, D., Carrillo-salinas, F., Chan, W., Chen, H., Dawson, R., Demambro, V., D’hont, J., Dibb, K. M., Eudy, J. D. & 93 others, Gan, L., Gao, J., Gonzales, A., Guntur, A. R., Guo, H., Harms, D. W., Harrington, A., Hentges, K. E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C. B., Li, L., Lindner, V., Liu, X., Lopez-castejon, G., Loudon, A., Lowe, J., Jerome-majewska, L. A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M. P., Ray, D., Redder, R. J., Rosen, C. J., Ross, N., Ruhe, M. T., Ryzhova, L., Salvador, A. M., Alam, S. S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A. W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B. J., Wright, C. S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D. J., Hochepied, T., Thomas, P., Parker-thornburg, J., Adamson, A. D., Yoshiki, A., Schmouth, J., Golovko, A., Thompson, W. R., Lloyd, K. C. K., Wood, J. A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J. M. & Burgio, G., 26 Aug 2019, In: Genome biology. 20, 1, 171.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Control of the inflammasome by the ubiquitin system

    Lopez‐castejon, G., 2019, In: The FEBS Journal.

    Research output: Contribution to journalArticlepeer-review

  9. Published

    Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: A multi-center evaluation

    Gurumurthy, C. B., O'Brien, A. R., Quadros, R. M., Adams, J., Alcaide, P., Ayabe, S., Ballard, J., Batra, S. K., Beauchamp, M-C., Becker, K. A., Bernas, G., Brough, D., Carrillo-Salinas, F., Chan, W., Chen, H., Dawson, R., Demambro, V., D'Hont, J., Dibb, K. M., Eudy, J. D. & 93 others, Gan, L., Gao, J., Gonzales, A., Guntur, A. R., Guo, H., Harms, D. W., Harrington, A., Hentges, K. E., Humphreys, N., Imai, S., Ishii, H., Iwama, M., Jonasch, E., Karolak, M., Keavney, B., Khin, N-C., Konno, M., Kotani, Y., Kunihiro, Y., Lakshmanan, I., Larochelle, C., Lawrence, C. B., Li, L., Lindner, V., Liu, X-D., Lopez-Castejon, G., Loudon, A., Lowe, J., Jerome-Majewska, L. A., Matsusaka, T., Miura, H., Miyasaka, Y., Morpurgo, B., Motyl, K., Nabeshima, Y-I., Nakade, K., Nakashiba, T., Nakashima, K., Obata, Y., Ogiwara, S., Ouellet, M., Oxburgh, L., Piltz, S., Pinz, I., Ponnusamy, M. P., Ray, D., Redder, R. J., Rosen, C. J., Ross, N., Ruhe, M. T., Ryzhova, L., Salvador, A. M., Alam, S. S., Sedlacek, R., Sharma, K., Smith, C., Staes, K., Starrs, L., Sugiyama, F., Takahashi, S., Tanaka, T., Trafford, A. W., Uno, Y., Vanhoutte, L., Vanrockeghem, F., Willis, B. J., Wright, C. S., Yamauchi, Y., Yi, X., Yoshimi, K., Zhang, X., Zhang, Y., Ohtsuka, M., Das, S., Garry, D. J., Hochepied, T., Thomas, P., Parker-Thornburg, J., Adamson, A. D., Yoshiki, A., Schmouth, J-F., Golovko, A., Thompson, W. R., Lloyd, K. C. K., Wood, J. A., Cowan, M., Mashimo, T., Mizuno, S., Zhu, H., Kasparek, P., Liaw, L., Miano, J. M. & Burgio, G., 2019, In: Genome biology.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

    Tapia, V. S., Daniels, M. J. D., Palazón-riquelme, P., Dewhurst, M., Luheshi, N. M., Rivers-auty, J., Green, J., Redondo-castro, E., Kaldis, P., Lopez-castejon, G. & Brough, D., 2019, In: Journal of Biological Chemistry. 294, 21, p. 8325-8335 11 p.

    Research output: Contribution to journalArticlepeer-review

  11. 2018
  12. Published

    Chloride regulates dynamic NLRP3-dependent ASC oligomerisation and inflammasome priming

    Green, J., Yu, S., Martín-Sánchez, F., Pelegrin, P., Lopez-Castejon, G., Lawrence, C. B. & Brough, D., 2 Oct 2018, In: Proceedings of the National Academy of Sciences. 115, 40, p. E9371-E9380

    Research output: Contribution to journalArticlepeer-review

  13. Published

    USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation

    Palazón-Riquelme, P., Worboys, J. D., Green, J., Valera, A., Martín-Sánchez, F., Pellegrini, C., Brough, D. & López-Castejón, G., Oct 2018, In: EMBO reports. 19, 10, e44766.

    Research output: Contribution to journalArticlepeer-review

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