Prof Emma Crosbie BSc, MBChB (Hons), PhD, MRCOG

Professor of Gynaecological Oncology

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Research interests

Endometrial cancer is the fourth most common cancer affecting women in the UK, behind breast, lung and colon cancer. The incidence of endometrial cancer has been rising steadily over the past twenty years. At the same time, the number of women dying from the disease has increased, despite improvements in overall survival. Endometrial cancer ranks highest amongst all cancers in its association with obesity. My group is interested in exploring this link with obesity with a view to developing new treatment and prevention strategies for endometrial cancer.  

Current projects include:

  • The role of obesity and weight loss on the endometrium
  • The effectiveness of intra-uterine progestin plus weight loss for the treatment of obese women with endometrial precancer /early stage cancer
  • Endometrial cancer prevention through lifestyle change and progestin treatment
  • Screening for Lynch syndrome-associated endometrial cancer and understanding its biology
  • Developing novel non-invasive detection tools for endometrial cancer
  • Risk prediction modelling for the identification of women at greatest risk of endometrial cancer to enable targeted prevention strategies
  • Diagnostic and prognostic biomarkers for endometrial cancer

Other research interests include human papillomavirus (HPV)-associated lower genital tract neoplasia, particularly CIN and cervical cancer. My group is involved in:

  • Testing interventions designed to improve uptake of cervical screening 
  • Investigating the clinical utility of new HPV tests
  • Urine for HPV detection and improving uptake in cervical screening 

We are also involved in projects exploring novel biomarkers for ovarian cancer detection

Methodological knowledge

Clinical trial design and execution

Novel intervention pilot studies

Translational research

Projects

Research and projects