Dr Donald Ward PhD, SFHEA

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Publications

  1. 2019
  2. Published

    Sensing Extracellular Calcium – An Insight into the Structure and Function of the Calcium-Sensing Receptor (CaSR)

    Ward, D., 24 Oct 2019, Calcium Signalling. p. 1031-1063 33 p. (Advances in Experimental Medicine and Biology; vol. 1131).

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

  3. Published

    Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

    Centeno, P., Herberger, A., Mun, H-C., Tu, C., Nemeth, E. F., Chang, W., Conigrave, A. D. & Ward, D., 16 Oct 2019, In: Nature Communications. 10, 12 p., 4693.

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Identification of Serine-875 as an Inhibitory Phosphorylation Site in the Calcium-Sensing Receptor.

    Ward, D., 2019, In: Molecular pharmacology.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Treatment of Autosomal Dominant Hypocalcemia Type 1 with the Calcilytic NPSP795 (SHP635).

    Ward, D., 2019, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

    Research output: Contribution to journalArticlepeer-review

  6. 2016
  7. Published

    The vascular Ca2+-sensing receptor regulates blood vessel tone and blood pressure

    Schepelmann, M., Yarova, P. L., Lopez-Fernandez, I., Davies, T. S., Brennan, S. C., Edwards, P. J., Aggarwal, A., Graça, J., Rietdorf, K., Matchkov, V., Fenton, R. A., Chang, W., Krssak, M., Stewart, A., Broadley, K. J., Ward, D., Price, S. A., Edwards, D. H., Kemp, P. J. & Riccardi, D., 1 Feb 2016, In: American journal of physiology. Cell physiology. 310, 3, p. C193-204 ajpcell.00248.2015.

    Research output: Contribution to journalArticlepeer-review

  8. 2015
  9. Published

    Pathophysiologic changes in extracellular pH modulate parathyroid calcium-sensing receptor activity and secretion via a histidine-independent mechanism

    Campion, K., Mccormick, W., Warwicker, J., Bin khayat, M. E., Atkinson-Dell, R., Steward, M., Delbridge, LW., Mun, HC., Conigrave, AD. & Ward, D., Sep 2015, In: Journal of the American Society of Nephrology. 26, 9, p. 2163-2171 8 p., ASN.2014070653.

    Research output: Contribution to journalArticlepeer-review

  10. Published

    Calcium-sensing receptor antagonists abrogate airway hyperresponsiveness and inflammation in allergic asthma

    Yarova, P. L., Stewart, A. L., Sathish, V., Britt Jr, R. D., Thompson, M. A., Lowe, A. P. P., Freeman, M., Aravamudan, B., Kita, H., Brennan, S. C., Schepelmann, M., Davies, T., Yung, S., Cholisoh, Z., Kidd, E. J., Ford, W. R., Broadley, K. J., Rietdorf, K., Chang, W., Bin Khayat, M. E. & 7 others, Ward, D. T., Corrigan, C. J., Ward, J. P. T., Kemp, P. J., Pabelick, C. M., Prakash, Y. S. & Riccardi, D., 22 Apr 2015, In: Science Translational Medicine. 7, 284, p. 284ra60

    Research output: Contribution to journalArticlepeer-review

  11. 2014
  12. Published

    The inhibitory effect of simvastatin and aspirin on histamine responsiveness in human vascular endothelial cells.

    Absi, M., Bruce, J. I. & Ward, D. T., 1 Apr 2014, In: American journal of physiology. Cell physiology. 306, 7, p. C679-C686

    Research output: Contribution to journalArticlepeer-review

  13. 2013
  14. Published

    Molecular and clinical analysis of a neonatal severe hyperparathyroidism case caused by a stop mutation in the calcium-sensing receptor extracellular domain representing in effect a human 'knockout'

    Ward, D. T., Mughal, M. Z., Ranieri, M., Dvorak-Ewell, M. M., Valenti, G. & Riccardi, D., Jul 2013, In: European Journal of Endocrinology. 169, 1, p. -K7

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Increased endothelin-1 responsiveness in human coronary artery smooth muscle cells exposed to 1,25-dihydroxyvitamin D(3)

    Absi, M. & Ward, D. T., 1 Apr 2013, In: American Journal of Physiology: Cell Physiology. 304, 7, p. C666-C672

    Research output: Contribution to journalArticlepeer-review

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