David graduated in Medicine from London University (St. Bartholomew’s) in 1976 and moved to Manchester to study Psychiatry in 1979. After completing his training in general psychiatry , he arranged a temporary secondment to Clinical Genetics in 1986 to pursue an interest in the genetic aspects of psychiatric disorders, and ended up 'going native'. He is now a senior lecturer and honorary consultant in neuropsychiatric genetics.
His research interests are concerned mainly with the neuropsychiatric aspects of Huntington's disease (HD), and with the psychological and social impact of predictive DNA testing for late-onset genetic disorders. He set up the UK’s first multidisciplinary management clinic for HD, currently the largest contributing site to the European HD Network (EHDN) case registry, and is actively involved in a number of European and World-wide research projects and clinical trials. He is a member of the Scientific Review Committee of the EHDN, leads the EHDN Behavioural Phenotype Working Group and is a former Secretary-General of the World Federation of Neurology Research Group on HD. He is co-Director of the MSc programme and teaches on the Clinical Genetics and Advanced Genetic Counselling modules.