Prof David Brough PhD

Professor

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Publications

  1. 2021
  2. Accepted/In press

    Applying agile, iterative co-design principles to the development of a smartphone app for people living with dementia

    Fox, S., Brown, L. J. E., Antrobus, S., Brough, D., Drake, R., Jury, F., Leroi, I., Parry-Jones, A. & Machin, M., 8 Oct 2021, (Accepted/In press) In: JMIR mHealth and uHealth.

    Research output: Contribution to journalArticlepeer-review

  3. 2020
  4. Accepted/In press

    Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation

    Lawrence, C. B., Rivers-Auty, J., Tapia Olivares, V., White, C., Daniels, M., Drinkall, S., Kennedy, P., Spence, H., Yu Shi, A., Green, J., Hoyle, C., Cook, J., Bradley, A., Mather, A., Peters, R., Tzeng, T-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 4 Dec 2020, (Accepted/In press) In: Journal of Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  5. Published

    Inhibiting the NLRP3 Inflammasome

    Freeman, S., Brough, D. & El-Sharkawy, L., 25 Nov 2020, In: Molecules. 25, 5533, 14 p.

    Research output: Contribution to journalReview articlepeer-review

  6. Published

    LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

    Green, J., Swanton, T., Morris, L., El-Sharkawy, L., Cook, J., Yu Shi, A., Beswick, J., Adamson, A., Humphreys, N., Bryce, R., Freeman, S., Lawrence, C. B. & Brough, D., 20 Nov 2020, In: eLife. 2020, 9, e59704.

    Research output: Contribution to journalArticlepeer-review

  7. E-pub ahead of print

    Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification

    Yu Shi, A., Green, J., Wellens, R., Lopez-Castejon, G. & Brough, D., 3 Nov 2020, (E-pub ahead of print) In: The FEBS Journal.

    Research output: Contribution to journalArticlepeer-review

  8. Published
  9. Published
  10. Published

    Selective inhibition of the K+ efflux sensitive NLRP3 pathway by Cl- channel modulation

    Swanton, T., Beswick, J., Hammadi, H., Morris, L., Williams, D., De Cesco, S., El-sharkawy, L., Yu, S., Green, J., Davis, J., Lawrence, C., Brough, D. & Freeman, S., 12 Oct 2020, In: Chemical Science. 11, 43, p. 11720-11728 9 p.

    Research output: Contribution to journalArticlepeer-review

  11. Published

    Priming is dispensable for NLRP3 inflammasome activation in human monocytes in vitro

    Gritsenko, A., Yu, S., Martín-Sánchez, F., Díaz Del Olmo, I., Nichols, E-M., Davis, D. M., Brough, D. & Lopez-Castejon, G., 30 Sep 2020, In: Frontiers in Immunology. 11, 565924.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Value of dynamic clinical and biomarker data for mortality risk prediction in COVID-19: a multicentre retrospective cohort study

    Berzuini, C., Hannan, C., King, A., Vail, A., O'Leary, C., Brough, D., Galea, J., Ogungbenro, K., Wright, M., Pathmanaban, O., Hulme, S., Allan, S., Bernardinelli, L. & Patel, H. C., 23 Sep 2020, In: BMJ Open. 10, 9, p. e041983

    Research output: Contribution to journalArticlepeer-review

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