Prof Daniel Brison PhD, FRCPath

Research interests

Human embryo research:

• Single embryo and single cell transcriptome and epigenome profiling of human embryo development
• Regulation of metabolism and cell fate in early human development
• human embryo implantation using in in vitro model systems
• The impact of the environment on early human development and implantation

Assisted reproduction research:

• Outcomes of assisted reproduction treatment
• Assessing the impact of new technologies in assisted reproduction
• The growth and long term health of children born by assisted reproduction 
• The impact of cryopreservation on the developmental competence of human oocytes

Sperm research:

• The impact of environmental and lifestyle exposures on male fertility and sperm DNA
• Sperm micromotors for detection and treatment of ovarian cancer
• The impact of the male contraceptive pill on sperm quality

Stem cell research

• Generation of clinical grade embryonic stem cells suitable for clinical transplantation
• Proteomic and metabolomic analysis of embryonic stem cell growth and differentiation to chondrocyte