Dr Constantinos Demonacos

Senior Lecturer

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Research interests

Exploiting endoplasmic reticulum stress and unfolded protein response signaling in the immunotherapy of cancer, neurodegenerative and autoimmune diseases 

The role of reactive oxygen species in cancer cells' evasion of immunosurveillance

Mechanisms of cell cycle regulation.

Novel biological networks involving transcriptional co-factors in the regulation of cell cycle and apoptosis.

Regulatory mechanisms controlling the malignant transformation through nuclear and mitochondrial inter-genomic signalling pathways.

Methodological knowledge

Molecular Biology (regulation of gene expression)
Biochemistry (protein-protein interaction)
Molecular Pharmacology (dissection of signaling pathways with therapeutic targeting potential)

Projects

Research and projects

No current projects are available for public display