Dr Christopher Hoyle

Research Associate

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Publications

  1. 2022
  2. Published

    Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages

    Hoyle, C., Green, J., Allan, S. & Brough, D., 1 Apr 2022, In: Immunology. 165, 4

    Research output: Contribution to journalArticlepeer-review

  3. 2021
  4. Published

    NLRP3 activation in response to disrupted endocytic traffic

    Lee, B., Hoyle, C., Green, J., Wellens, R., Martín-Sánchez, F., Williams, D., Seoane Denicola, P., Bennett, H., Adamson, A., Lopez-Castejon, G., Lowe, M. & Brough, D., 16 Sep 2021, In: bioRxiv.

    Research output: Contribution to journalArticle

  5. 2020
  6. Accepted/In press

    Zinc status alters Alzheimer's disease progression through NLRP3-dependent inflammation

    Lawrence, C. B., Rivers-Auty, J., Tapia Olivares, V., White, C., Daniels, M., Drinkall, S., Kennedy, P., Spence, H., Yu Shi, A., Green, J., Hoyle, C., Cook, J., Bradley, A., Mather, A., Peters, R., Tzeng, T-C., Gordon, M. J., Beattie, J. H., Brough, D. & Lawrence, C. B., 4 Dec 2020, (Accepted/In press) In: Journal of Neuroscience.

    Research output: Contribution to journalArticlepeer-review

  7. Accepted/In press

    The NLRP3 inflammasome as a sensor of organelle dysfunction

    Seoane Denicola, P., Lee, B., Hoyle, C., Yu Shi, A., Lopez-Castejon, G., Lowe, M. & Brough, D., 18 Sep 2020, (Accepted/In press) In: Journal of Cell Biology.

    Research output: Contribution to journalArticlepeer-review

  8. Published

    Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture

    Hoyle, C., Redondo Castro, E., Cook, J., Tzeng, T-C., Allan, S., Brough, D. & Lemarchand, E., 23 May 2020, In: Immunology. 161, 1, p. 39-52

    Research output: Contribution to journalArticlepeer-review

  9. 2018
  10. Published

    Small, Thin Graphene Oxide Is Anti-inflammatory Activating Nuclear Factor Erythroid 2-Related Factor 2 via Metabolic Reprogramming

    Hoyle, C., Rivers-Auty, J., Lemarchand, E., Vranic, S., Wang, E., Buggio, M., Rothwell, N. J., Allan, S. M., Kostarelos, K. & Brough, D., 26 Dec 2018, In: ACS Nano. 12, 12, p. 11949-11962 14 p.

    Research output: Contribution to journalArticlepeer-review

  11. 2016
  12. Published

    The effect of bisphosphonate treatment on osteoclast precursor cells in postmenopausal osteoporosis: The TRIO study

    Gossiel, F., Hoyle, C., McCloskey, E. V., Naylor, K. E., Walsh, J., Peel, N. & Eastell, R., Nov 2016, In: Bone. 92, p. 94-99 6 p.

    Research output: Contribution to journalArticlepeer-review