Prof Charles Mccollum

Research interests

Professor McCollum’s research is in arterial and venous disease. He leads a research team of fellows, scientists and technicians, and his collaborations are with various disciplines including particularly epidemiology, neuro-imaging, mental health and stroke medicine. Research teams are assembled to investigate the role of cerebral emboli in dementia, migraine and dialysis-related brain injury.
Special research interests include:

Arterial Disease

• Carotid surgery, angioplasty and stenting
• Extra-cranial and upper limb arterial disease
• Thoraco-abdominal and peri-renal aortic aneurysm
• Endovascular aneurysm repair (EVAR)
• Screening for abdominal aortic aneurysm (AAA)
• The indication to repair AAA perioperative risk and predicition of survival
• Paradoxical embolism
• Cerebral embolism

Venous disease

• Deep vein thrombosis
• Venous thromboembolism
• Chronic venous insufficiency
• Varicose veins (VVs)
• Leg ulcers or venous ulcers
• Novel treatments for VVs
• Compression therapy
• Symptoms caused by pelvic vein incompetence in women

Other

• Clinical trials in vascular disease and dementia
• Stroke in young adults
• Migraine and migraine with aura
• Cerebral injury in haemodialysis
• Autologous blood transfusion
• Blood transfusion strategies in surgery
• A novel blood transfusion trigger

Keywords

• Vascular disease
• Arterial thrombosis
• Venous thrombosis
• Deep vein thrombosis (DVT)
• Pulmonary embolism (PE)
• Cardio-pulmonary exercise testing (CPET)
• Cerebral perfusion
• Paradoxical embolism
• Carotid artery disease
• Ischaemia - reperfusion injury
• Cerebral emboli
• Migraine
• Migraine with aura
• Venous disease
• Leg ulceration
• Autologous blood transfusion
• Vascular dementia
• Alzheimer's disease
• Inflammatory responses

Methodological knowledge

• Complex vascular surgery
• Multi-centre clinical trials
• Population studies (cardiovascular epidemiology)
• Autologous blood transfusion strategies
• Investigation of cerebral perfusion