Dr Bruno M SimõesPhD

Research Fellow

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Publications

  1. Article › Research › Peer-reviewed
  2. Published

    Ethnicity influences breast cancer stem cells' drug resistance

    Kamal, M., Nafie, E. H. O., Elsers, S., Alanwar, S., Ibrahim, R., Farag, F., Mlees, M., Simões, B. M., Spence, K., Santiago-Gómez, A., Salem, M. L. & Clarke, R. B., Jul 2018, In : Breast Journal. 24, 4, p. 701-703 3 p.

    Research output: Contribution to journalArticle

  3. Published

    FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

    McClements, L., Annett, S., Yakkundi, A., O'Rourke, M., Valentine, A., Moustafa, N., Alqudah, A., Simões, B. M., Furlong, F., Short, A., McIntosh, S. A., McCarthy, H. O., Clarke, R. B. & Robson, T., 2019, In : BMC Cancer. 19, 1, 351.

    Research output: Contribution to journalArticle

  4. Published

    Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.

    Giordano, C., Chemi, F., Panza, S., Bonofiglio, D., Lanzino, M., Cordella, A., Campana, A., Hashim, A., Rizza, P., Győrffy, B., Simões, B. M., Clarke, R., Weisz, A., Catalano, S. & Andò, S., 12 Jan 2016, In : Oncotarget. 7, 2, p. 1262-1275 13 p.

    Research output: Contribution to journalArticle

  5. Published

    Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells.

    Aires, A., Ocampo, S. M., Simões, B. M., Josefa Rodríguez, M., Couleaud, P., Spence, K., Latorre, A., Miranda, R., Somoza, Á., Clarke, R., Carrascosa, J. L. & Cortajarena, A. L., 12 Feb 2016, In : Nanotechnology. 27, 6, p. 065103

    Research output: Contribution to journalArticle

  6. Published

    Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling

    Harrison, H., Simões, B. M., Rogerson, L., Howell, S. J., Landberg, G. & Clarke, R. B., 8 Mar 2013, In : Breast Cancer Research. 15, 2, R21.

    Research output: Contribution to journalArticle

  7. Published

    PAK4 regulates stemness and progression in endocrine resistant ERpositive metastatic breast cancer

    Santiago-Gómez, A., Kedward, T., M Simoes, B., Dragoni, I., NicAmhlaoibh, R., Trivier, E., Sabin, V., Gee, J. M., Sims, A. H., Howell, S. J. & Clarke, R. B., 28 Aug 2019, In : Cancer Letters. 11 p., 10.1016/j.canlet.2019.05.014.

    Research output: Contribution to journalArticle

  8. Published

    Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

    Eyre, R., Alférez, D. G., Spence, K., Kamal, M., Shaw, F. L., Simões, B. M., Santiago-Gómez, A., Sarmiento-Castro, A., Bramley, M., Absar, M., Saad, Z., Chatterjee, S., Kirwan, C., Gandhi, A., Armstrong, A. C., Wardley, A. M., O'Brien, C. S., Farnie, G., Howell, S. J. & Clarke, R. B., 28 Sep 2016, In : Journal of Mammary Gland Biology and Neoplasia.

    Research output: Contribution to journalArticle

  9. Published

    Recent Advances Reveal IL-8 Signalling as a Potential Key to Targeting Breast Cancer Stem Cells

    Singh, J., Simões, B. M., Howell, S., Farnie, G. & Clarke, RB., 30 Aug 2013, In : Breast Cancer Research. 15, 4, p. 210 210.

    Research output: Contribution to journalArticle

  10. Published

    Sox2 promotes tamoxifen resistance in breast cancer cells

    Piva, M., Domenici, G., Iriondo, O., Rábano, M., Simões, B. M., Comaills, V., Barredo, I., López-Ruiz, J. A., Zabalza, I., Kypta, R. & Vivanco, M. D. M., Jan 2014, In : EMBO Molecular Medicine . 6, 1, p. 66-79 13 p.

    Research output: Contribution to journalArticle

  11. Published

    Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms.

    Singh, J. K., Farnie, G., Bundred, N. J., Simões, B. M., Shergill, A., Landberg, G., Howell, S. J. & Clarke, R. B., 1 Feb 2013, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 19, 3, p. 643-656 13 p.

    Research output: Contribution to journalArticle

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Research output: Contribution to journalArticle