Dr Bruno M SimõesPhD

Research Fellow

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Publications

  1. 2015
  2. Published

    The role of steroid hormones in breast cancer stem cells

    Simões, B. M., Alferez, D., Howell, S. & Clarke, R., 17 Sep 2015, In : Endocrine-related cancer. 22 (6):T177-86, 6, p. 177-186 9 p., ERC-15-0350.

    Research output: Contribution to journalArticle

  3. Published

    Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity.

    M Simoes, B., O'Brien, C., Eyre, R., Silva, A., Yu, L., Sarmiento Castro, A., Alferez-Castro, D., Spence, K., Santiago-Gomez, A., Chemi, F., Acar, A., Gandhi, A., Howell, A., Brennan, K., Rydén, L., Catalano, S., Andó, S., Gee, J., Ucar, A., Sims, A. H. & 5 others, Marangoni, E., Farnie, G., Landberg, G., Howell, S. & Clarke, R. B., 29 Sep 2015, In : Cell Reports. 12, 12, p. 1968-1977 9 p.

    Research output: Contribution to journalArticle

  4. 2016
  5. Published

    A Role for Notch Signalling in Breast Cancer and Endocrine Resistance.

    Acar, A., Simões, B. M., Clarke, R. B. & Brennan, K., 2016, In : Stem cells international. 2016

    Research output: Contribution to journalArticle

  6. Published

    Leptin as a mediator of tumor-stromal interactions promotes breast cancer stem cell activity.

    Giordano, C., Chemi, F., Panza, S., Bonofiglio, D., Lanzino, M., Cordella, A., Campana, A., Hashim, A., Rizza, P., Győrffy, B., Simões, B. M., Clarke, R., Weisz, A., Catalano, S. & Andò, S., 12 Jan 2016, In : Oncotarget. 7, 2, p. 1262-1275 13 p.

    Research output: Contribution to journalArticle

  7. Published

    Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells.

    Aires, A., Ocampo, S. M., Simões, B. M., Josefa Rodríguez, M., Couleaud, P., Spence, K., Latorre, A., Miranda, R., Somoza, Á., Clarke, R., Carrascosa, J. L. & Cortajarena, A. L., 12 Feb 2016, In : Nanotechnology. 27, 6, p. 065103

    Research output: Contribution to journalArticle

  8. Published

    Cisplatin selects for stem-like cells in osteosarcoma by activating notch signaling

    Yu, L., Fan, Z., Fang, S., Yang, J., Gao, T., Simões, B. M., Eyre, R., Guo, W. & Clarke, R. B., 20 Apr 2016, In : Oncotarget.

    Research output: Contribution to journalArticle

  9. Published

    Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

    Eyre, R., Alférez, D. G., Spence, K., Kamal, M., Shaw, F. L., Simões, B. M., Santiago-Gómez, A., Sarmiento-Castro, A., Bramley, M., Absar, M., Saad, Z., Chatterjee, S., Kirwan, C., Gandhi, A., Armstrong, A. C., Wardley, A. M., O'Brien, C. S., Farnie, G., Howell, S. J. & Clarke, R. B., 28 Sep 2016, In : Journal of Mammary Gland Biology and Neoplasia.

    Research output: Contribution to journalArticle

  10. 2017
  11. Published

    Targeting IL-1 beta-Wnt signalling to prevent breast cancer colonisation in the bone microenvironment

    Eyre, R., Alferez, D., Santiago-Gomez, A., Spence, K., McConnell, J., Simoes, B., Hart, C., Lefley, D., Tulotta, C., Gurney, A., Howell, S., Brown, M., Sims, A., Farnie, G., Ottewell, P. & Clarke, R., Dec 2017, In : Clinical and Experimental Metastasis. 34, 8, p. 493-493

    Research output: Contribution to journalMeeting Abstract

  12. 2018
  13. Published

    Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors

    M Simoes, B., Kohler, B., Clarke, R. B., Stringer, J., Novak Frazer, L., Young, K., Richardson, R., Zucchini, G., Armstrong, A. & Howell, S., 2018, In : Therapeutic Advances in Medical Oncology. 10

    Research output: Contribution to journalArticle

  14. Published

    The Role of Steroid Hormones in Breast and Effects on Cancer Stem Cells

    Alferez-Castro, D., M Simoes, B., Howell, S. & Clarke, R., 2018, In : Current Stem Cell Reports.

    Research output: Contribution to journalArticle

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Research output: Contribution to journalArticle