Dr Bruno M SimõesPhD

Research Fellow

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Publications

  1. 2011
  2. Published

    Cancer stem cells in the human mammary gland and regulation of their differentiation by estrogen

    Simões, B. M. & Vivanco, M. D., Aug 2011, In : Future Oncology. 7, 8, p. 995-1006 11 p.

    Research output: Contribution to journalArticle

  3. Published

    Effects of estrogen on the proportion of stem cells in the breast

    Simões, B. M., Piva, M., Iriondo, O., Comaills, V., López-Ruiz, J. A., Zabalza, I., Mieza, J. A., Acinas, O. & Vivanco, M. D. M., Aug 2011, In : Breast Cancer Research and Treatment. 129, 1, p. 23-35 12 p.

    Research output: Contribution to journalArticle

  4. 2012
  5. Published

    A detailed mammosphere assay protocol for the quantification of breast stem cell activity

    Shaw, F. L., Harrison, H., Spence, K., Ablett, M. P., Simões, B. M., Farnie, G. & Clarke, R. B., Jun 2012, In : Journal of Mammary Gland Biology and Neoplasia. 17, 2, p. 111-117 6 p.

    Research output: Contribution to journalArticle

  6. 2013
  7. Published

    Targeting CXCR1/2 significantly reduces breast cancer stem cell activity and increases the efficacy of inhibiting HER2 via HER2-dependent and -independent mechanisms.

    Singh, J. K., Farnie, G., Bundred, N. J., Simões, B. M., Shergill, A., Landberg, G., Howell, S. J. & Clarke, R. B., 1 Feb 2013, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 19, 3, p. 643-656 13 p.

    Research output: Contribution to journalArticle

  8. Published

    Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling

    Harrison, H., Simões, B. M., Rogerson, L., Howell, S. J., Landberg, G. & Clarke, R. B., 8 Mar 2013, In : Breast Cancer Research. 15, 2, R21.

    Research output: Contribution to journalArticle

  9. Published

    Recent Advances Reveal IL-8 Signalling as a Potential Key to Targeting Breast Cancer Stem Cells

    Singh, J., Simões, B. M., Howell, S., Farnie, G. & Clarke, RB., 30 Aug 2013, In : Breast Cancer Research. 15, 4, p. 210 210.

    Research output: Contribution to journalArticle

  10. Published

    Targeting IL-8 signalling to inhibit breast cancer stem cell activity

    Singh, J. K., Simões, B. M., Clarke, R. B. & Bundred, N. J., Nov 2013, In : Expert Opinion on Therapeutic Targets. 17, 11, p. 1235-1241 6 p.

    Research output: Contribution to journalArticle

  11. Published

    Enrichment of human osteosarcoma stem cells based on hTERT transcriptional activity

    Yu, L., Liu, S., Zhang, C., Zhang, B., Simões, B. M., Eyre, R., Liang, Y., Yan, H., Wu, Z., Guo, W. & Clarke, R., Dec 2013, In : Oncotarget. 4, 12, p. 2326-2338 12 p.

    Research output: Contribution to journalArticle

  12. 2014
  13. Published

    Sox2 promotes tamoxifen resistance in breast cancer cells

    Piva, M., Domenici, G., Iriondo, O., Rábano, M., Simões, B. M., Comaills, V., Barredo, I., López-Ruiz, J. A., Zabalza, I., Kypta, R. & Vivanco, M. D. M., Jan 2014, In : EMBO Molecular Medicine . 6, 1, p. 66-79 13 p.

    Research output: Contribution to journalArticle

  14. Published

    Breast cancer stem-like cell activity correlates with tumour progression to metastasis but not with clinical or tumour characteristics

    Howell, SJ., Alferez, D., Spence, K., Eyre, R., Shaw, F., Simões, B. M., Santiago-Gomez, A., Bramley, M., Absar, M., Saad, Z., Chatterjee, S., Kirwan, C., Gandhi, A., Armstrong, AC., Wardley, AM., Farnie, G. & Clarke, R., Dec 2014.

    Research output: Contribution to conferencePoster

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Research output: Contribution to journalArticle