Dr Bruno M SimõesPhD

Research Fellow

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  1. 2019
  2. Published

    PAK4 regulates stemness and progression in endocrine resistant ERpositive metastatic breast cancer

    Santiago-Gómez, A., Kedward, T., M Simoes, B., Dragoni, I., NicAmhlaoibh, R., Trivier, E., Sabin, V., Gee, J. M., Sims, A. H., Howell, S. J. & Clarke, R. B., 28 Aug 2019, In : Cancer Letters. 11 p., 10.1016/j.canlet.2019.05.014.

    Research output: Contribution to journalArticle

  3. Published

    Reprogramming of Amino Acid Transporters to Support Aspartate and Glutamate Dependency Sustains Endocrine Resistance in Breast Cancer

    Bacci, M., Lorito, N., Ippolito, L., Ramazzotti, M., Luti, S., Romagnoli, S., Parri, M., Bianchini, F., Cappellesso, F., Virga, F., Gao, Q., M Simoes, B., Marangoni, E., Martin, L-A., Comito, G., Ferracin, M., Giannoni, E., Mazzone, M., Chiarugi, P. & Morandi, A., 2 Jul 2019, In : Cell Reports. 28, 1, p. 104-118

    Research output: Contribution to journalArticle

  4. Published

    A Sox2-Sox9 signalling axis maintains human breast luminal progenitor and breast cancer stem cells

    Domenici, G., Aurrekoetxea-Rodríguez, I., Simões, B. M., Rábano, M., Lee, S. Y., Millán, J. S., Comaills, V., Oliemuller, E., López-Ruiz, J. A., Zabalza, I., Howard, B. A., Kypta, R. M. & Vivanco, M. DM., 2019, In : Oncogene.

    Research output: Contribution to journalArticle

  5. Published

    FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4

    McClements, L., Annett, S., Yakkundi, A., O'Rourke, M., Valentine, A., Moustafa, N., Alqudah, A., Simões, B. M., Furlong, F., Short, A., McIntosh, S. A., McCarthy, H. O., Clarke, R. B. & Robson, T., 2019, In : BMC Cancer. 19, 1, 351.

    Research output: Contribution to journalArticle

  6. 2018
  7. Published

    Ethnicity influences breast cancer stem cells' drug resistance

    Kamal, M., Nafie, E. H. O., Elsers, S., Alanwar, S., Ibrahim, R., Farag, F., Mlees, M., Simões, B. M., Spence, K., Santiago-Gómez, A., Salem, M. L. & Clarke, R. B., Jul 2018, In : Breast Journal. 24, 4, p. 701-703 3 p.

    Research output: Contribution to journalArticle

  8. Published

    Acquired Resistance of ER-Positive Breast Cancer to Endocrine Treatment Confers an Adaptive Sensitivity to TRAIL through Posttranslational Downregulation of c-FLIP

    Piggott, L., Silva, A., Robinson, T., Santiago-Gómez, A., Simões, B. M., Becker, M., Fichtner, I., Andera, L., Young, P., Morris, C., Barrett-Lee, P., Alchami, F., Piva, M., Vivanco, M. DM., Clarke, R. B., Gee, J. & Clarkson, R., 15 May 2018, In : Clinical Cancer Research. 24, 10, p. 2452-2463 12 p.

    Research output: Contribution to journalArticle

  9. Published

    Estrogenicity of essential oils is not required to relieve symptoms of urogenital atrophy in breast cancer survivors

    M Simoes, B., Kohler, B., Clarke, R. B., Stringer, J., Novak Frazer, L., Young, K., Richardson, R., Zucchini, G., Armstrong, A. & Howell, S., 2018, In : Therapeutic Advances in Medical Oncology. 10

    Research output: Contribution to journalArticle

  10. Published

    The Role of Steroid Hormones in Breast and Effects on Cancer Stem Cells

    Alferez-Castro, D., M Simoes, B., Howell, S. & Clarke, R., 2018, In : Current Stem Cell Reports.

    Research output: Contribution to journalArticle

  11. 2017
  12. Published

    Targeting IL-1 beta-Wnt signalling to prevent breast cancer colonisation in the bone microenvironment

    Eyre, R., Alferez, D., Santiago-Gomez, A., Spence, K., McConnell, J., Simoes, B., Hart, C., Lefley, D., Tulotta, C., Gurney, A., Howell, S., Brown, M., Sims, A., Farnie, G., Ottewell, P. & Clarke, R., Dec 2017, In : Clinical and Experimental Metastasis. 34, 8, p. 493-493

    Research output: Contribution to journalMeeting Abstract

  13. 2016
  14. Published

    Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis

    Eyre, R., Alférez, D. G., Spence, K., Kamal, M., Shaw, F. L., Simões, B. M., Santiago-Gómez, A., Sarmiento-Castro, A., Bramley, M., Absar, M., Saad, Z., Chatterjee, S., Kirwan, C., Gandhi, A., Armstrong, A. C., Wardley, A. M., O'Brien, C. S., Farnie, G., Howell, S. J. & Clarke, R. B., 28 Sep 2016, In : Journal of Mammary Gland Biology and Neoplasia.

    Research output: Contribution to journalArticle

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Research output: Contribution to journalArticle