Prof Brian Bigger PhD

The Bone Marrow Functionally Contributes to Liver Fibrosis

Russo, F. P., Alison, M. R., Bigger, B. W., Amofah, E., Florou, A., Amin, F., Bou-Gharios, G., Jeffery, R., Iredale, J. P. & Forbes, S. J., Jun 2006, In: Gastroenterology. 130, 6, p. 1807-1821 14 p.

Research output: Contribution to journal › Article › peer-review

RecET driven chromosomal gene targeting to generate a RecA deficient Escherichia coli strain for Cre mediated production of minicircle DNA

Tolmachov, O., Palaszewski, I., Bigger, B. & Coutelle, C., 10 Mar 2006, In: BMC Biotechnology. 6, 17.

Research output: Contribution to journal › Article › peer-review

Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX

Bigger, B., Siapati, E. K., Mistry, A., Waddington, S. N., Nivsarkar, M. S., Jacobs, L., Perrett, R., Holder, M. V., Ridler, C., Kemball-Cook, G., Ali, R. R., Forbes, S. J., Coutelle, C., Wright, N., Alison, M., Thrasher, A. J., Bonnet, D. & Themis, M., Jan 2006, In: Gene Therapy. 13, 2, p. 117-126 9 p.

Research output: Contribution to journal › Article › peer-review

Oncogenesis following delivery of a nonprimate lentiviral gene therapy vector to fetal and neonatal mice

Themis, M., Waddington, S. N., Schmidt, M., von Kalle, C., Wang, Y., Al-Allaf, F., Gregory, L. G., Nivsarkar, M., Themis, M., Holder, M. V., Buckley, S. M. K., Dighe, N., Ruthe, A. T., Mistry, A., Bigger, B., Rahim, A., Nguyen, T. H., Trono, D., Thrasher, A. J. & Coutelle, C., Oct 2005, In: Molecular Therapy. 12, 4, p. 763-771 8 p.

Research output: Contribution to journal › Article › peer-review

Comparison of HIV- and EIAV-based vectors on their efficiency in transducing murine and human hematopoietic repopulating cells

Siapati, E. K., Bigger, B. W., Miskin, J., Chipchase, D., Parsley, K. L., Mitrophanous, K., Themis, M., Thrasher, A. J. & Bonnet, D., Sep 2005, In: Molecular Therapy. 12, 3, p. 537-546 9 p.

Research output: Contribution to journal › Article › peer-review

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy

Waddington, S. N., Nivsarkar, M. S., Mistry, A. R., Buckley, S. M. K., Kemball-Cook, G., Mosley, K. L., Mitrophanous, K., Radcliffe, P., Holder, M. V., Brittan, M., Georgiadis, A., Al-Allaf, F., Bigger, B. W., Gregory, L. G., Terence Cook, H., Ali, R. R., Thrasher, A., Tuddenham, E. G. D., Themis, M. & Coutelle, C., 1 Nov 2004, In: Blood. 104, 9, p. 2714-2721 7 p.

Research output: Contribution to journal › Article › peer-review

Highly efficient EIAV-mediated in utero gene transfer and expression in the major muscle groups affected by Duchenne muscular dystrophy

Bigger, B., Gregory, L. G., Waddington, S. N., Holder, M. V., Mitrophanous, K. A., Buckley, S. M. K., Mosley, K. L., Bigger, B. W., Ellard, F. M., Walmsley, L. E., Lawrence, L., Al-Allaf, F., Kingsman, S., Coutelle, C. & Themis, M., Jul 2004, In: Gene Therapy. 11, 14, p. 1117-1125 8 p.

Research output: Contribution to journal › Article › peer-review

Development of a Self-assembling Nuclear Targeting Vector System Based on the Tetracycline Repressor Protein

Vaysse, L., Harbottle, R., Bigger, B., Bergau, A., Tolmachov, O. & Coutelle, C., 13 Feb 2004, In: Journal of Biological Chemistry. 279, 7, p. 5555-5564 9 p.

Research output: Contribution to journal › Article › peer-review

Hepatic stem cells: From inside and outside the liver?

Alison, M. R., Vig, P., Russo, F., Bigger, B. W., Amofah, E., Themis, M. & Forbes, S., Feb 2004, In: Cell Proliferation. 37, 1, p. 1-21 20 p.

Research output: Contribution to journal › Article › peer-review