Prof Brian Bigger PhD

Professor of Cell and Gene Therapy

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Collaborators and affiliated staff

Group Members and Affiliated Staff

  • Dr Simon Jones - Consultant, Head of Willink Biochemical Genetics Unit
  • Dr Rob Wynn - Consultant, Head of Bone Marrow Transplantation Unit
  • Dr Becki Holley - Senior Postdoctoral Associate
  • Dr Claire O'Leary - Postdoctoral Associate
  • Dr Stuart Ellison -Postdoctoral Associate
  • Mr Kenny Yu - Speciality Registrar Neurosurgery/PhD student
  • Mr Ricky Pal -Speciality Registrar ENT/MD student
  • Miss Ai Yin Liao - Research Technician/part time PhD
  • Miss Helen Parker -PhD Student
  • Mr Saam Yoshani - PhD Student
  • Miss Helene Gleitz - PhD Student




  • Dr Cathy Merry, University of Manchester. Heparan sulphate and cellular interactions in neurodegenerative diseases
  • Dr Maria Canal, University of Manchester. Circadian profiling in MPS disease
  • Dr James Fildes, University of Manchester. Immunology in lysosomal disease
  • Professsor Nancy Rothwell, University of Manchester. Microglial interactions with brain tumours
  • Mr Ian Kamaly and Mr Omar Pathmanaban - Neurosurgery, Salford Royal NHS Foundation Trust. Brain tumour treatment development
  • Imagen Biotech Ltd


  • Professor Adrian Thrasher and Professor Bobby Gaspar, UCL. Stem cell gene therapy for lysosomal diseases
  • Professor Frits Wijburg, AMC Amsterdam. Biomarker development for lysosomal diseases
  • Professor Alexey Pshezhetsky, Sainte Justine Children's Hospital, Montreal, Canada. Gene therapy for MPSIIIC


Job Opportunities

We offer laboratory placements for motivated high quality project students on Manchester University Medical undergraduate or postgraduate MSc and MRes courses and will consider self-funded internships for excellent non-clinical or clinical candidates wishing to gain laboratory experience in the field.

Funded posts are advertised on the University jobsite and national websites such as