Dr Brahim Achour

Research Associate

Affiliations:
ORCID: 0000-0002-2595-5626
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Publications

41 - 50 out of 58Page size: 10
  1. 2018
  2. Published

    GASP and FASP are Complementary for LC-MS/MS Proteomic Analysis of Drug-Metabolizing Enzymes and Transporters in Pig Liver

    Howard, M., Achour, B., Al-Majdoub, Z., Rostami-Hodjegan, A. & Barber, J., 30 Nov 2018, In: Proteomics. 18, 24, 1800200.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/pmic.201800200 10.1002/pmic.201800200
  3. 2019
  4. Published

    Quantitative mass spectrometry-based proteomics in the era of model-informed drug development: Applications in translational pharmacology and recommendations for best practice

    Elkhateeb, E., Vasilogianni, A. M., Alrubia, S., Al-Majdoub, Z., Couto, N., Howard, M., Barber, J., Rostami-Hodjegan, A. & Achour, B., 2019, In: Pharmacology and Therapeutics.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.pharmthera.2019.107397 10.1016/j.pharmthera.2019.107397
  5. Published

    Toward a Consensus on Applying Quantitative Liquid Chromatography-Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

    Prasad, B., Achour, B., Artursson, P., Hop, C., Lai, Y., Smith, P. C., Barber, J., Wiśniewski, J. R., Spellman, D., Uchida, Y., Zientek, M., Unadkat, J. D. & Rostami-Hodjegan, A., 2019, In: Clinical Pharmacology & Therapeutics. 106, 3, p. 525-543 19 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1002/cpt.1537
  6. Published

    Response to “Determining Allele-Specific Protein Expression (ASPE) Using a Novel Quantitative Concatamer Based Proteomics Method”

    Achour, B., Rostami-Hodjegan, A. & Barber, J., 4 Jan 2019, In: J. Proteome Res.. 18, 1, p. 574-574

    Research output: Contribution to journal › Letter › peer-review

    DOI: 10.1021/acs.jproteome.8b00871
  7. Published

    Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics

    Couto, N., Al-Majdoub, Z., Achour, B., Wright, P., Rostami-Hodjegan, A. & Barber, J., 4 Feb 2019, In: Molecular Pharmaceutics. 16, 2, p. 632-647 16 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1021/acs.molpharmaceut.8b00941
  8. Published

    Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients

    Al-Majdoub, Z., Al Feteisi, H., Achour, B., Warwood, S., Neuhoff, S., Rostami-Hodjegan, A. & Barber, J., 4 Mar 2019, In: Molecular Pharmaceutics. 16, 3, p. 1220-1233 14 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1021/acs.molpharmaceut.8b01189
  9. Published

    The molecular stethoscope: RNA of drug metabolising enzymes in circulating vesicles correlates with their specific protein content in the liver

    Achour, B., Al-Majdoub, Z., Lea, K., Schageman, J. & Rostami-Hodjegan, A., 16 Sep 2019.

    Research output: Contribution to conference › Poster

  10. Published

    Methods and apparatus for quantifying protein abundance in tissues via cell free ribonucleic acids in liquid biopsy

    Rostami-Hodjegan, A., Achour, B. & Rothman, J. E., 3 Oct 2019, IPC No. C12Q 1/68, World Intellectual Property Organization, Patent No. WO 2019/191297 A1, 27 Mar 2018, Priority date 28 Mar 2018

    Research output: Patent

  11. 2020
  12. Published

    Characterization of CYP2B6 K262R Allelic Variants by Quantitative Allele-Specific Proteomics using a QconCAT Standard

    Barber, J., Russell, M. R., Rostami-Hodjegan, A. & Achour, B., 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 178, 112901.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.jpba.2019.112901
  13. Published

    Proteomic characterisation of drug metabolising enzymes and drug transporters in pig liver

    Elmorsi, Y., Al Feteisi, H., Al-Majdoub, Z., Barber, J., Rostami-Hodjegan, A. & Achour, B., 2020, In: Xenobiotica.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1080/00498254.2020.1763513
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Research Explorer downloads

319
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

Research output: Contribution to journal › Article › peer-review

234
In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

Research output: Contribution to journal › Article › peer-review

171
Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

Research output: Contribution to journal › Article › peer-review

106
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

Research output: Contribution to journal › Article › peer-review

100
Identification and Quantification of Blood-Brain Barrier Transporters in Isolated Rat Brain Microvessels

Research output: Contribution to journal › Article › peer-review