Dr Brahim Achour

Research Associate

Affiliations:
ORCID: 0000-0002-2595-5626
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Publications

31 - 40 out of 46Page size: 10
  1. 2015
  2. Published

    How LC-MS Proteomics is Revolutionizing PBPK Modelling and Simulation

    Achour, B. & Rostami-Hodjegan, A., 18 Feb 2015.

    Research output: Contribution to conference › Other

  3. Published

    Variations in LC-MS methods for absolute quantification of cytochrome P450 and uridine 5’-diphospho-glucuronosyltransferase enzymes in human tissue: A comparative cost analysis

    Feteisi, H. A., Achour, B., Barber, J. & Rostami-Hodjegan, A., Jan 2015.

    Research output: Contribution to conference › Poster

  4. Published

    Label-Free Method for Profiling Human Liver Enzymes: Validation with QconCAT

    Achour, B., Lanucara, F., Feteisi, H. A., Barber, J. & Rostami-Hodjegan, A., 2015.

    Research output: Contribution to conference › Poster

  5. Published

    Laboratory differences in relative expression factors generated for intestinal P-glycoprotein and Breast Cancer Resistance Protein: Relevance to in vitro-in vivo extrapolation

    Harwood, M. D., Achour, B., Neuhoff, S., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 2015.

    Research output: Contribution to conference › Poster

  6. Published

    Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Oswald, S., Busch, D., Weiss, F., Hammer, H., Joos, T. O., Poetz, O., Wortelboer, H., Steeg, E. V. D., Achour, B., Rostami-Hodjegan, A. & Artursson, P., 2015.

    Research output: Contribution to conference › Poster

  7. 2014
  8. Published

    A Cross-Laboratory Comparison of Caco-2 and Human Intestinal Drug Transporter Protein Abundances

    Harwood, M. D., Achour, B., Courbebaisse, Y., Russell, M. R., Neuhoff, S., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., Oct 2014.

    Research output: Contribution to conference › Poster

  9. Published

    Expression of Hepatic Drug-Metabolizing Cytochrome P450 & Uridine 5ꞌ-Glucuronosyltransferase Enzymes and their Inter-Correlations: Meta-Analysis & Experimental Study

    Achour, B., Barber, J. & Rostami-Hodjegan, A., 2014.

    Research output: Contribution to conference › Poster

  10. Published

    Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Inter-Correlations: A Meta-Analysis.

    Achour, B., Barber, J. & Rostami-Hodjegan, A., 2014, In : Drug Metabolism and Disposition. 42, 8, p. 1349-1356 7 p.

    Research output: Contribution to journal › Article

    DOI: 10.1124/dmd.114.058834
  11. Published

    Protein expression of various hepatic uridine 5'-diphosphate glucuronosyltransferase (UGT) enzymes and their inter-correlations: A meta-analysis

    Achour, B., Rostami-Hodjegan, A. & Barber, J., 2014, In : Biopharmaceutics and Drug Disposition. 35, p. 353-361 9 p.

    Research output: Contribution to journal › Article

    DOI: 10.1002/bdd.1906
  12. Published

    Simultaneous quantification of the abundance of several cytochrome P450 and uridine 5′-diphospho-glucuronosyltransferase enzymes in human liver microsomes using multiplexed targeted proteomics

    Achour, B., Russell, M. R., Barber, J. & Rostami-Hodjegan, A., 2014, In : Drug Metabolism and Disposition. 42, 4, p. 500-510 10 p.

    Research output: Contribution to journal › Article

    DOI: 10.1124/dmd.113.055632
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Research Explorer downloads

244
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

Research output: Contribution to journal › Article

182
In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

Research output: Contribution to journal › Article

95
Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

Research output: Contribution to journal › Article

50
Data generated by quantitative LC-MS proteomics are only the start and not the endpoint: Optimization of QconCAT-based measurement of hepatic UDP-glucuronosyltransferase enzymes with reference to catalytic activity

Research output: Contribution to journal › Article

41
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

Research output: Contribution to journal › Article