Dr Brahim Achour

Research Associate

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Publications

  1. 2016
  2. Published

    Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Busch, D., Oswald, S., Weiss, F., Hammer, H., Poetz, O., Joos, T. O., Wortelboer, H. M., Steeg, E. V. D., Achour, B., Rostami-Hochaghan, A. & Artursson, P., 15 Jul 2016, In: Drug Metabolism Reviews. 48, S1, p. 98-98 1 p.

    Research output: Contribution to journalMeeting Abstract

  3. Published

    In vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratroy Comparison of Transporter Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

    Harwood, M. D., Achour, B., Neuhoff, S., Russell, M. R., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 31 Jan 2016, In: Drug Metabolism and Disposition. 44, 3, p. 297-307 11 p.

    Research output: Contribution to journalArticlepeer-review

  4. Published

    Establishing the Relationship between mRNA Expression and Protein Abundance for Seven Transporters in Human Small Intestine: A Pilot Study

    Harwood, M. D., Gibson, S. L., Achour, B., Davies, P. J., Carlson, G. L., Rostami-Hodjegan, A. & Warhurst, G., 28 Jan 2016.

    Research output: Contribution to conferencePoster

  5. Published

    In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

    Harwood, M. D., Achour, B., Neuhoff, S., Russell, M. R., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 2016, In: Drug Metabolism and Disposition. 44, 3, p. 476-480 5 p.

    Research output: Contribution to journalArticlepeer-review

  6. 2015
  7. Published
  8. Published

    Ten years of QconCATs: Application of multiplexed quantification to small medically-relevant proteomes

    Achour, B., Al-Majdoub, Z., Al Feteisi, H., Elmorsi, Y., Rostami-Hochaghan, A. & Barber, J., 30 Nov 2015, In: International Journal of Mass Spectrometry. 391, 2015, p. 93-104 12 p.

    Research output: Contribution to journalArticlepeer-review

  9. Published
  10. Published
  11. Published

    Towards more Realistic Clinical Trial Simulation: Establishing Inter-Correlations between Several Cytochrome P450 Enzyme Abundances in Human Liver

    Wedagedera, J. R., Abduljalil, K., Cain, T., Achour, B., Pathak, S., Dunlavey, M., Jamei, M. & Rostami-Hodjegan, A., 2 Jun 2015.

    Research output: Contribution to conferencePoster

  12. Published

    Meta-analysis of Expression of Hepatic Organic Anion Transporting Polypeptide (OATP) Transporters in Cellular Systems Relative to Human Liver Tissue

    Badée, J., Achour, B., Rostami-Hochaghan, A. & Galetin, A., Apr 2015, In: Drug Metabolism and Disposition. 43, 4, p. 424-432 9 p.

    Research output: Contribution to journalArticlepeer-review