Dr Brahim Achour

Research Associate

Affiliations:
ORCID: 0000-0002-2595-5626
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Publications

31 - 40 out of 58Page size: 10
  1. 2016
  2. Published

    Protein quantification of human hepatic drug transporters and metabolizing enzymes: an inter-laboratory and methodological comparison

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Busch, D., Oswald, S., Weiss, F., Hammer, H., Poetz, O., Joos, T. O., Wortelboer, H. M., Steeg, E. V. D., Achour, B., Rostami-Hochaghan, A. & Artursson, P., 15 Jul 2016, In: Drug Metabolism Reviews. 48, S1, p. 98-98 1 p.

    Research output: Contribution to journal › Meeting Abstract

  3. Published

    In vitro-In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratroy Comparison of Transporter Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells

    Harwood, M. D., Achour, B., Neuhoff, S., Russell, M. R., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 31 Jan 2016, In: Drug Metabolism and Disposition. 44, 3, p. 297-307 11 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1124/dmd.115.067371 10.1124/dmd.115.067371
  4. Published

    Establishing the Relationship between mRNA Expression and Protein Abundance for Seven Transporters in Human Small Intestine: A Pilot Study

    Harwood, M. D., Gibson, S. L., Achour, B., Davies, P. J., Carlson, G. L., Rostami-Hodjegan, A. & Warhurst, G., 28 Jan 2016.

    Research output: Contribution to conference › Poster

  5. Published

    In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

    Harwood, M. D., Achour, B., Neuhoff, S., Russell, M. R., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 2016, In: Drug Metabolism and Disposition. 44, 3, p. 476-480 5 p.

    Research output: Contribution to journal › Article › peer-review

  6. 2015
  7. Published

    Comparison of label-free and QconCAT quantitative proteomic methods for the quantification of human liver enzymes

    Feteisi, H. A., Lanucara, F., Barber, J., Rostami-Hodjegan, A. & Achour, B., Dec 2015.

    Research output: Contribution to conference › Poster

  8. Published

    Ten years of QconCATs: Application of multiplexed quantification to small medically-relevant proteomes

    Achour, B., Al-Majdoub, Z., Al Feteisi, H., Elmorsi, Y., Rostami-Hochaghan, A. & Barber, J., 30 Nov 2015, In: International Journal of Mass Spectrometry. 391, 2015, p. 93-104 12 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1016/j.ijms.2015.08.003
  9. Published

    It is a matter of trust! Performing cross-laboratory-cross-technique comparisons in quantitative ADME proteomics

    Harwood, M., Achour, B., Wegler, C. & Rostami-Hochaghan, A., 29 Oct 2015.

    Research output: Contribution to conference › Other

  10. Published

    Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro-in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques

    Al Feteisi, H., Achour, B., Rostami-Hochaghan, A. & Barber, J., 24 Jun 2015, In: Expert Opinion on Drug Metabolism & Toxicology. 11, 9, p. 1357-1369 13 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1517/17425255.2015.1055245 10.1517/17425255.2015.1055245 10.1517/17425255.2015.1055245
  11. Published

    Towards more Realistic Clinical Trial Simulation: Establishing Inter-Correlations between Several Cytochrome P450 Enzyme Abundances in Human Liver

    Wedagedera, J. R., Abduljalil, K., Cain, T., Achour, B., Pathak, S., Dunlavey, M., Jamei, M. & Rostami-Hodjegan, A., 2 Jun 2015.

    Research output: Contribution to conference › Poster

  12. Published

    Meta-analysis of Expression of Hepatic Organic Anion Transporting Polypeptide (OATP) Transporters in Cellular Systems Relative to Human Liver Tissue

    Badée, J., Achour, B., Rostami-Hochaghan, A. & Galetin, A., Apr 2015, In: Drug Metabolism and Disposition. 43, 4, p. 424-432 9 p.

    Research output: Contribution to journal › Article › peer-review

    DOI: 10.1124/dmd.114.062034
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Research Explorer downloads

317
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

Research output: Contribution to journal › Article › peer-review

233
In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

Research output: Contribution to journal › Article › peer-review

165
Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

Research output: Contribution to journal › Article › peer-review

104
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

Research output: Contribution to journal › Article › peer-review

96
Identification and Quantification of Blood-Brain Barrier Transporters in Isolated Rat Brain Microvessels

Research output: Contribution to journal › Article › peer-review