Dr Brahim Achour

Research Associate

View graph of relations

Publications

  1. 2018
  2. Published

    Data generated by quantitative LC-MS proteomics are only the start and not the endpoint: Optimization of QconCAT-based measurement of hepatic UDP-glucuronosyltransferase enzymes with reference to catalytic activity

    Achour, B., Dantonio, A. L., Niosi, M., Novak, J. J., Al-Majdoub, Z., Goosen, T. C., Rostami-Hodjegan, A. & Barber, J., 1 Jun 2018, In: Drug Metabolism and Disposition. 46, 6, p. 805-812 8 p.

    Research output: Contribution to journalArticlepeer-review

  3. Published

    Implications of inter-correlation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: A case study with repaglinide

    Doki, K., Darwich, A., Achour, B., Tornio, A., Backman, J. T. & Rostami-Hochaghan, A., May 2018, In: British Journal of Clinical Pharmacology. 84, 5, p. 972–986 15 p.

    Research output: Contribution to journalArticlepeer-review

  4. 2017
  5. Published

    Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

    Achour, B., Dantonio, A., Niosi, M., Novak, J. J., Fallon, J. K., Barber, J., Smith, P. C., Rostami-Hochaghan, A. & Goosen, T. C., 1 Oct 2017, In: Drug Metabolism and Disposition. 45, 10, p. 1102-1112 11 p.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    Quantitative Proteomic Analysis of Drug Transporters in Human Blood Brain Barrier

    Al-Majdoub, Z., Al Feteisi, H., Achour, B., Rostami-Hochaghan, A. & Barber, J., 19 Sep 2017.

    Research output: Contribution to conferencePoster

  7. Published

    Quantitative Proteomic Analysis of Drug Transporters in Human Blood Brain Barrier

    Al-Majdoub, Z., Al Feteisi, H., Achour, B., Rostami-Hodjegan, A. & Barber, J., 19 Sep 2017, HUPO2017.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  8. Published

    Cross-laboratory evaluation of UDP-glucuronosyltransferase (UGT) abundances and correlation with catalytic activity

    Achour, B., Dantonio, A. L., Niosi, M., Novak, J. J., Fallon, J. K., Barber, J., Smith, P. C., Rostami-Hochaghan, A. & Goosen, T. C., 26 Jun 2017.

    Research output: Contribution to conferencePoster

  9. Published

    Variability in protein quantification using different mass spectrometry-based proteomics workflows

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Oswald, S., Busch, D., Weiss, F., Hammer, H., Poetz, O., Wortelboer, H. M., Steeg, E. V. D., Achour, B., Rostami-Hochaghan, A. & Artursson, P., 26 Jun 2017.

    Research output: Contribution to conferencePoster

  10. Published

    Inter-laboratory variability in mass spectrometry-based proteomics workflows

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Oswald, S., Gröer, C., Busch, D., Weiss, F., Hammer, H., Joos, T. O., Poetz, O., Wortelboer, H., Steeg, E. V. D., Achour, B., Rostami-Hochaghan, A. & Artursson, P., 21 May 2017.

    Research output: Contribution to conferencePoster

  11. Published

    Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

    Achour, B., Al Feteisi, H., Lanucara, F., Rostami-Hochaghan, A. & Barber, J., 11 May 2017, In: Drug Metabolism and Disposition. 45, 6, p. 666-675 10 p.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Variability in mass spectrometry-based quantification of clinically relevant drug transporters and drug metabolizing enzymes

    Wegler, C., Gaugaz, F. Z., Andersson, T. B., Wiśniewski, J. R., Busch, D., Gröer, C., Oswald, S., Weiss, F., Hammer, H., Joos, T. O., Poetz, O., Achour, B., Rostami-Hochaghan, A., Steeg, E. V. D., Wortelboer, H. M. & Artursson, P., 2017, In: Molecular Pharmaceutics. 14, 9, p. 3142-3151 10 p.

    Research output: Contribution to journalArticlepeer-review