Dr Brahim Achour

Research Associate

Affiliations:
ORCID: 0000-0002-2595-5626
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Publications

21 - 30 out of 46Page size: 10
  1. 2016
  2. Published

    Establishing the Relationship between mRNA Expression and Protein Abundance for Seven Transporters in Human Small Intestine: A Pilot Study

    Harwood, M. D., Gibson, S. L., Achour, B., Davies, P. J., Carlson, G. L., Rostami-Hodjegan, A. & Warhurst, G., 28 Jan 2016.

    Research output: Contribution to conference › Poster

  3. Published

    In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

    Harwood, M. D., Achour, B., Neuhoff, S., Russell, M. R., Carlson, G., Warhurst, G. & Rostami-Hodjegan, A., 2016, In : Drug Metabolism and Disposition. 44, 3, p. 476-480 5 p.

    Research output: Contribution to journal › Article

  4. 2015
  5. Published

    Comparison of label-free and QconCAT quantitative proteomic methods for the quantification of human liver enzymes

    Feteisi, H. A., Lanucara, F., Barber, J., Rostami-Hodjegan, A. & Achour, B., Dec 2015.

    Research output: Contribution to conference › Poster

  6. Published

    Ten years of QconCATs: Application of multiplexed quantification to small medically-relevant proteomes

    Achour, B., Al-Majdoub, Z., Al Feteisi, H., Elmorsi, Y., Rostami-Hochaghan, A. & Barber, J., 30 Nov 2015, In : International Journal of Mass Spectrometry. 391, 2015, p. 93-104 12 p.

    Research output: Contribution to journal › Article

    DOI: 10.1016/j.ijms.2015.08.003
  7. Published

    It is a matter of trust! Performing cross-laboratory-cross-technique comparisons in quantitative ADME proteomics

    Harwood, M., Achour, B., Wegler, C. & Rostami-Hochaghan, A., 29 Oct 2015.

    Research output: Contribution to conference › Other

  8. Published

    Translational value of liquid chromatography coupled with tandem mass spectrometry-based quantitative proteomics for in vitro-in vivo extrapolation of drug metabolism and transport and considerations in selecting appropriate techniques

    Al Feteisi, H., Achour, B., Rostami-Hochaghan, A. & Barber, J., 24 Jun 2015, In : Expert Opinion on Drug Metabolism & Toxicology. 11, 9, p. 1357-1369 13 p.

    Research output: Contribution to journal › Article

    DOI: 10.1517/17425255.2015.1055245 10.1517/17425255.2015.1055245 10.1517/17425255.2015.1055245
  9. Published

    Towards more Realistic Clinical Trial Simulation: Establishing Inter-Correlations between Several Cytochrome P450 Enzyme Abundances in Human Liver

    Wedagedera, J. R., Abduljalil, K., Cain, T., Achour, B., Pathak, S., Dunlavey, M., Jamei, M. & Rostami-Hodjegan, A., 2 Jun 2015.

    Research output: Contribution to conference › Poster

  10. Published

    Meta-analysis of Expression of Hepatic Organic Anion Transporting Polypeptide (OATP) Transporters in Cellular Systems Relative to Human Liver Tissue

    Badée, J., Achour, B., Rostami-Hochaghan, A. & Galetin, A., Apr 2015, In : Drug Metabolism and Disposition. 43, 4, p. 424-432 9 p.

    Research output: Contribution to journal › Article

    DOI: 10.1124/dmd.114.062034
  11. Published

    Choice of LC-MS methods for the absolute quantification of drug-metabolizing enzymes and transporters in human tissue: A comparative cost analysis

    Al Feteisi, H., Achour, B., Barber, J. & Rostami-Hochaghan, A., Mar 2015, In : The A A P S Journal. 17, 2, p. 438-446 9 p.

    Research output: Contribution to journal › Article

    DOI: 10.1208/s12248-014-9712-6 10.1208/s12248-014-9712-6
  12. Published

    Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

    Harwood, M. D., Achour, B., Russell, M. R., Carlson, G. L., Warhurst, G. & Rostami-Hodjegan, A., 28 Feb 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 110, p. 27-33 7 p.

    Research output: Contribution to journal › Article

    DOI: doi:10.1016/j.jpba.2015.02.043
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Research Explorer downloads

244
Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

Research output: Contribution to journal › Article

182
In vitro-in vivo extrapolation scaling factors for intestinal P-glycoprotein and breast cancer resistance protein: Part II. The impact of cross-laboratory variations of intestinal transporter relative expression factors on predicted drug disposition

Research output: Contribution to journal › Article

95
Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

Research output: Contribution to journal › Article

50
Data generated by quantitative LC-MS proteomics are only the start and not the endpoint: Optimization of QconCAT-based measurement of hepatic UDP-glucuronosyltransferase enzymes with reference to catalytic activity

Research output: Contribution to journal › Article

41
Quantitative Characterization of Major Hepatic UDP-Glucuronosyltransferase Enzymes in Human Liver Microsomes: Comparison of Two Proteomic Methods and Correlation with Catalytic Activity

Research output: Contribution to journal › Article