Dr Brahim Achour

Research Associate

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Publications

  1. Article › Research › Peer-reviewed
  2. Published

    Alternative fusion protein strategies to express recalcitrant QconCAT proteins for quantitative proteomics of human drug metabolizing enzymes and transporters

    Russell, M. R., Achour, B., McKenzie, E. A., Lopez, R., Harwood, M. D., Rostami-Hodjegan, A. & Barber, J., 6 Dec 2013, In : Journal of Proteome Research. 12, 12, p. 5934-5942 8 p.

    Research output: Contribution to journalArticle

  3. Published

    Application of an LC-MS/MS Method for the Simultaneous Quantification of Human Intestinal Transporter Proteins Absolute Abundance using a QconCAT Technique

    Harwood, M. D., Achour, B., Russell, M. R., Carlson, G. L., Warhurst, G. & Rostami-Hodjegan, A., 28 Feb 2015, In : Journal of Pharmaceutical and Biomedical Analysis. 110, p. 27-33 7 p.

    Research output: Contribution to journalArticle

  4. Published
  5. Published
  6. Published

    Data generated by quantitative LC-MS proteomics are only the start and not the endpoint: Optimization of QconCAT-based measurement of hepatic UDP-glucuronosyltransferase enzymes with reference to catalytic activity

    Achour, B., Dantonio, A. L., Niosi, M., Novak, J. J., Al-Majdoub, Z., Goosen, T. C., Rostami-Hodjegan, A. & Barber, J., 1 Jun 2018, In : Drug Metabolism and Disposition. 46, 6, p. 805-812 8 p.

    Research output: Contribution to journalArticle

  7. Published

    Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Inter-Correlations: A Meta-Analysis.

    Achour, B., Barber, J. & Rostami-Hodjegan, A., 2014, In : Drug Metabolism and Disposition. 42, 8, p. 1349-1356 7 p.

    Research output: Contribution to journalArticle

  8. Published
  9. Published

    Global Proteomic Analysis of Human Liver Microsomes: Rapid Characterization and Quantification of Hepatic Drug-Metabolizing Enzymes

    Achour, B., Al Feteisi, H., Lanucara, F., Rostami-Hochaghan, A. & Barber, J., 11 May 2017, In : Drug Metabolism and Disposition. 45, 6, p. 666-675 10 p.

    Research output: Contribution to journalArticle

  10. Published

    Identification and Quantification of Blood-Brain Barrier Transporters in Isolated Rat Brain Microvessels

    Al Feteisi, H., Al-Majdoub, Z., Achour, B., Couto, N., Rostami-Hodjegan, A. & Barber, J., Sep 2018, In : Journal of neurochemistry. 146, 6, p. 670-685

    Research output: Contribution to journalArticle

  11. Published

    Implications of inter-correlation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: A case study with repaglinide

    Doki, K., Darwich, A., Achour, B., Tornio, A., Backman, J. T. & Rostami-Hochaghan, A., May 2018, In : British Journal of Clinical Pharmacology. 84, 5, p. 972–986 15 p.

    Research output: Contribution to journalArticle

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