Dr Anthony Tighe BSc, PhD

Research Fellow

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  1. 2021
  2. Accepted/In press

    TP53 loss initiates chromosomal instability in fallopian tube epithelial cells

    Bronder, D., Tighe, A., Wangsa, D., Zong, D., Meyer, T. J., Wardenaar, R., Minshall, P., Hirsch, D., Heselmeyer-Haddad, K., Nelson, L., Spierings, D., Mcgrail, J., Cam, M., Nussenzweig, A., Foijer, F., Riedel, T. & Taylor, S., 20 Sep 2021, (Accepted/In press) In: DMM Disease Models and Mechanisms.

    Research output: Contribution to journalArticlepeer-review

  3. 2020
  4. Published

    A living biobank of ovarian cancer ex vivo models reveals profound mitotic heterogeneity

    Nelson, L., Tighe, A., Golder, A., Littler, S., Bakker, B., Moralli, D., Baker, S. M., Donaldson, I., Spierings, D. C. J., Wardenaar, R., Neale, B., Burghel, G., Winter-Roach, B., Edmondson, R., Clamp, A., Jayson, G., Desai, S., Green, C. M., Hayes, A., Foijer, F. & 2 others, Morgan, R. & Taylor, S., 13 Feb 2020, In: Nature Communications. 11, 1, 822.

    Research output: Contribution to journalArticlepeer-review

  5. 2019
  6. Published

    DNA replication vulnerabilities render ovarian cancer cells sensitive to poly(ADP-ribose) glycohydrolase inhibitors

    Taylor, S., Pillay, N., Tighe, A., Nelson, L., Littler, S., Coulson-Gilmer, C., Bah, N., Golder, A., James, D., Smith, K., Jordan, A., Morgan, R. D., Ogilvie, D. & Jackson, D., 2019, In: Cancer Cell|Cancer Cell. 35, 3, p. 519-533

    Research output: Contribution to journalArticlepeer-review

  7. 2018
  8. Published

    The p38α stress kinase suppresses aneuploidy tolerance by inhibiting Hif-1α

    Taylor, S., Simões-Sousa, S., Littler, S., Thompson, S., Minshall, P., Whalley, H., Bakker, B., Belkot, K., Moralli, D., Bronder, D., Tighe, A., Spierings, D., Bah, N., Graham, J., Nelson, L., Green, C., Foijer, F. & Townsend, P., 16 Oct 2018, In: Cell Reports. 25, 3, p. 749-760.e6

    Research output: Contribution to journalArticlepeer-review

  9. 2016
  10. Published

    Inhibition of Bcl-xL sensitizes cells to mitotic blockers but not mitotic drivers

    Bennett, A., Sloss, O., Topham, C., Nelson, L., Tighe, A. & Taylor, S., 8 Oct 2016, In: Open Biology.

    Research output: Contribution to journalArticlepeer-review

  11. 2015
  12. Published

    MYC Is a Major Determinant of Mitotic Cell Fate

    Topham, C., Tighe, A., Ly, P., Bennett, A., Sloss, O., Nelson, L., Ridgway, R. A., Huels, D., Littler, S., Schandl, C., Sun, Y., Bechi, B., Procter, D. J., Sansom, O. J., Cleveland, D. W. & Taylor, S. S., 13 Jul 2015, In: Cancer Cell. 28, 1, p. 129-140

    Research output: Contribution to journalArticlepeer-review