Anthony Jones is professor of Neuro-rheumatology at Manchester University and leads the Human Pain Research Group. Whilst at the Hammersmith Hospital he pioneered the development of techniques to image neurochemical and metabolic brain responses to pain using Positron Emission Tomography. Over the last twenty years he has used a number of functional brain imaging techniques to understand that the normal and abnormal mechanisms of pain perception. There is now the exciting prospect of using some of the insights gained in these studies to develop new approaches to pharmacological and cognitive interventions for chronic pain. He also leads the International Association of Pain Musculoskletal Pain Taskforce and is leading the development of National and International Guidelines on the Integrated Management of Musculoskeletal Pain (jointly sponsored by the BSR and the IASP).