Prof Angeliki Malliri

Compartmentalisation of RAC1 Signalling

Boben Payapilly, A. & Malliri, A., Oct 2018, In : Current opinion in cell biology. 54, p. 50-56 6 p.

Research output: Contribution to journal › Article

TIAM1 antagonizes TAZ/YAP both in the destruction complex in the cytoplasm and in the nucleus to inhibit invasion of intestinal epithelial cells

Diamantopoulou, Z., White, G., Fadlullah Wilmot, M. Z. H., Dreger, M., Pickering, K., Maltas, J., Ashton, G., MacLeod, R., Baillie, G. S., Kouskoff, V., Lacaud, G., Murray, G. I., Sansom, O. J., Hurlstone, A. & Malliri, A., 8 May 2017, In : Cancer Cell. 31, 5, p. 621–634 14 p., e6.

Research output: Contribution to journal › Article

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

Myant, K. B., Cammareri, P., Hodder, M. C., Wills, J., Von Kriegsheim, A., Győrffy, B., Rashid, M., Polo, S., Maspero, E., Vaughan, L., Gurung, B., Barry, E., Malliri, A., Camargo, F., Adams, D. J., Iavarone, A., Lasorella, A. & Sansom, O. J., Feb 2017, In : EMBO Molecular Medicine . p. 181-197

Research output: Contribution to journal › Article

Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

Marei, H. & Malliri, A., 21 Jul 2016, In : Small GTPases.

Research output: Contribution to journal › Article

Proteomic Analysis of Rac1 Signalling Regulation by Guanine Nucleotide Exchange Factors

Marei, H., Carpy, A., Macek, B. & Malliri, A., 6 May 2016, In : Cell Cycle.

Research output: Contribution to journal › Article

Deregulation of Rho GTPases in cancer

Porter, A., Papaioannou, A. & Malliri, A., 28 Mar 2016, (Accepted/In press) In : Small GTPases.

Research output: Contribution to journal › Article

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

Marei, H., Carpy, A., Woroniuk, A., Vennin, C., White, G., Timpson, P., Macek, B. & Malliri, A., 2016, In : Nature Communications.

Research output: Contribution to journal › Article

GEFs: Dual regulation of Rac1 signaling

Hadir Marei1 & Malliri, A., 2016, In : Small GTPases.

Research output: Contribution to journal › Article

HUWE1 ubiquitylates and degrades the Rac activator TIAM1 promoting cell–cell adhesion disassembly, migration and invasion

Vaughan, L., Tan, C-T., Chapman, A., Nonaka, D., Mack, N., Smith, D., Booton, R., Hurlstone, A. & Malliri, A., 6 Jan 2015, In : Cell Reports. 10, 1

Research output: Contribution to journal › Article

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation

Whalley, H. J., Porter, A. P., Diamantopoulou, Z., White, G. R. M., Castañeda-Saucedo, E. & Malliri, A., 2015, In : Nature Communications.

Research output: Contribution to journal › Article