Dr Andrew Pierce

Research Fellow

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Publications

  1. 2020
  2. Accepted/In press

    EVI1 oncoprotein expression and CtBP1 association oscillate through the cell cycle

    Paredes, R., Schneider, M., Pearson, S., Teng, H-Y., Kelly, J., Pierce, A., Somervaille, T., Whetton, A. & Meyer, S., 5 Sep 2020, (Accepted/In press) In : Molecular Biology Reports.

    Research output: Contribution to journalArticlepeer-review

  3. Accepted/In press

    EVI1-phosphorylation at S436 regulates interactions with CtBP1 and DNMT3A and promotes self-renewal

    Paredes, R., Kelly, J., Geary, B., Almarzouq, B., Schneider, M., Pearson, S., Narayanan, P., Williamson, A., Lovell, S., Wiseman, D., Chadwick, J., Jones, N. J., Kustikova, O., Schambach, A., Garner, T., Amaral, F., Pierce, A., Stevens, A., Somervaille, T., Whetton, A. & 1 others, Meyer, S., 3 Aug 2020, (Accepted/In press) In : Cell Death and Disease.

    Research output: Contribution to journalArticlepeer-review

  4. 2019
  5. Published

    Oncogenic MYC amplifies mitotic perturbations

    Taylor, S., Littler, S., Sloss, O., Geary, B., Pierce, A. & Whetton, A., 28 Aug 2019, In : Open Biology.

    Research output: Contribution to journalArticlepeer-review

  6. Published

    AXL inhibition extinguishes primitive JAK2 mutated myeloproliferative neoplasm progenitor cells

    Pearson, S., Blance, R., Somervaille, T., Whetton, A. & Pierce, A., 24 Apr 2019, In : HemaSphere.

    Research output: Contribution to journalArticlepeer-review

  7. Published

    Proteomic analysis of an induced pluripotent stem cell model reveals strategies to treat Juvenile Myelomonocytic Leukaemia

    Pearson, S., Guo, B., Pierce, A., Azadbakht, N., Brazzatti, J. A., Patassini, S., Mulero-navarro, S., Meyer, S., Flotho, C., Gelb, B. D. & Whetton, A. D., 2019, In : Journal of Proteome Research.

    Research output: Contribution to journalArticlepeer-review

  8. 2018
  9. Published

    EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association

    Paredes, R., Schneider, M., Stevens, F., White, D., Williamson, A. J. K., Muter, J., Pearson, S., Kelly, J., Connors, K., Wiseman, D., Chadwick, J., Loffler, H., Teng, H. Y., Lovell, S., Unwin, R., Van De Vrugt, H. J., Smith, H., Kustikova, O., Schambach, A., Somervaille, T. & 3 others, Pierce, A., Whetton, A. & Meyer, S., 6 Sep 2018, In : Nucleic acids research. 46, 15, p. 7662-7674

    Research output: Contribution to journalArticlepeer-review

  10. 2017
  11. Published

    Acquired cross linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption

    Meyer, S., Stevens, F., Paredes, R., Schneider, M., Walker, M., Williamson, A., Gonzalez-Sanchez, M., Smetsers, S., Dalal, V., Teng, H-Y., White, D., Taylor, S., Muter, J., Pierce, A., De Leonibus, C., Rockx, D. AP., Rooimans, M., Spooncer, E., Stauffer, S., Biswas, K. & 5 others, Godthelp, B., Dorsman, J., Clayton, P., Sharan, S. K. & Whetton, A., 2017, In : CELL DEATH & DISEASE. 8, e2875.

    Research output: Contribution to journalArticlepeer-review

  12. Published

    Proteomic analysis of JAK2V617F induced changes identifies 2 potential new combinatorial therapeutic approaches

    Pearson, S., Williamson, A., Blance, R., Somervaille, T., Taylor, S., Azadbakht, N., Whetton, A. & Pierce, A., 2017, In : Leukemia.

    Research output: Contribution to journalArticlepeer-review

  13. 2016
  14. Published

    Development of a Selected Reaction Monitoring Mass Spectrometry-Based Assay to Detect Asparaginyl Endopeptidase Activity in Biological Fluids

    Dutta, A., Potier, D. N., Walker, M. J., Gray, O., Parker, C., Holland, M., Williamson, A. J. K., Pierce, A., Unwin, R., Krishnan, S., Saha, V. & Whetton, A., 23 Sep 2016, In : Oncotarget. 7

    Research output: Contribution to journalArticlepeer-review

  15. Published

    Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells

    Abraham, S. A., Hopcroft, L. E. M., Carrick, E., Drotar, M. E., Dunn, K., Williamson, A. J. K., Korfi, K., Baquero, P., Park, L. E., Scott, M. T., Pellicano, F., Pierce, A., Copland, M., Nourse, C., Grimmond, S. M., Vetrie, D., Whetton, A. & Holyoake, T. L., 16 Jun 2016, In : Nature. 534, 7607, p. 341-346 6 p.

    Research output: Contribution to journalArticlepeer-review

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