Why Is Research on Amyloid-ß Failing to Give New Drugs for Alzheimer’s Disease?

Doig, A., Del Castillo Frias, M., Berthoumieu, O., Tarus, B., Nasica-Labouze, J., Sterpone, F., Nguyen, P. H., Hooper, N. M., Faller, P. & Derreumaux, P. 19 Jul 2017 In : ACS Chemical Neuroscience. 8, 7, p. 1435-1437 3 p.

Research output: Research - peer-review › Article

Properties of Genes Essential for Mouse Development

Kabir, M., Barradas, A., Tzotzos , G. T., Hentges, K. & Doig, A. 2017 In : PLoS ONE. 12, 5, e0178273

Research output: Research - peer-review › Article

The secondary structure and glycosylation of mucus glycoproteins by Raman spectroscopies

Davies, H. S., Singh, P., Deckert-Gaudig, T., Deckert, V., Rousseau, K., Ridley, C. E., Dowd, S. E., Doig, A. J., Pudney, P. D. A., Thornton, D. J. & Blanch, E. W. 28 Oct 2016 In : Analytical chemistry.

Research output: Research - peer-review › Article

Determination of Protein Secondary Structure from Infrared Spectra Using Partial Least-Squares Regression

. Wilcox, K. E., Blanch, E. & Doig, A. 2016 In : Biochemistry. 55, 27, p. 3794−3802

Research output: Research - peer-review › Article

Frozen, but No Accident – Why the 20 Standard Amino Acids were Selected

Doig, A. 2016 In : FEBS Journal.

Research output: Research - peer-review › Article

Combined Experimental and Simulation Studies Suggest a Revised Mode of Action of the Anti-Alzheimer Disease Drug NQ-Trp

Berthoumieu, O., Nguyen, P. H., Derreaumaux, P., Faller, P., del Castillo-Frias, M. P., Ferre, S., Tarus, B., Nasica-Labouze, J., Noel, S., Saurel, O., Rampon, C. & Doig, A. J. Jul 2015 In : Chemistry: A European Journal.

Research output: Research - peer-review › Article

Properties of Protein Drug Target Classes

Bull, S. C. & Doig, A. J. 30 Mar 2015 In : P L o S One.

Research output: Research - peer-review › Article

Amyloid β Protein and Alzheimer’s Disease: When Computer Simulations Complement Experimental Studies

Nasica-Labouze, J. , Nguyen, P. H. , Laio, A. , Li, M. S. , Melchionna, S. , Mousseau, N. , Mu, Y. , Paravastu, A. , Pasquali, S. , Rosenman, D. J. , Strodel, B. , Tarus, B. , Sterpone, F. , Viles, J. H. , Zhang, T. , Wang, C. , Derreumaux, P. , Berthoumieu, O. , Buchete, N-V. , Coté, S. & 4 others De Simone, A., Doig, A. J., Faller, P. & Garcia, A. 2015 In : Chemical Reviews.

Research output: Research - peer-review › Article

Inhibition of Protein Aggregation and Amyloid Formation by Small Molecules

Doig, A. & Philippe, D. 2015 In : Current Opinion in Structural Biology. 30, p. 50-56 6 p.

Research output: Research - peer-review › Article

Molecular structure of the NQTrp inhibitor with the Alzheimer A1-28 monomer

Doig, A., Tarus, B., Nguyen, P. H., Berthoumieu, O., Faller, P. & Derreumaux, D. 2015 In : European Journal of Medicinal Chemistry. 91, p. 43-50 7 p.

Research output: Research - peer-review › Article