Dr Aleksandra Galetin

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Publications

  1. 2018
  2. Published

    In vitro–in vivo extrapolation of OATP1B-mediated drug–drug interactions in cynomolgus monkey

    Ufuk, A., Kosa, R. E., Gao, H., Bi, Y. A., Modi, S., Gates, D., Rodrigues, A. D., Tremaine, L. M., Varma, M. V. S., Houston, J. B. & Galetin, A. 1 Jun 2018 In : Journal of Pharmacology and Experimental Therapeutics. 365, 3, p. 688-699 12 p.

    Research output: Contribution to journalArticle

  3. Published

    Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury

    Kenna, J. G., Waterton, J. C., Baudy, A., Galetin, A., Hines, C. D. G., Hockings, P., Patel, M., Scotcher, D., Sourbron, S., Ziemian, S. & Schuetz, G. 21 Mar 2018 Drug-Induced Liver Toxicity. New York, NY: Humana Press, Inc., p. 627-651 25 p. (Methods in Pharmacology and Toxicology; no. 9781493976768)

    Research output: Chapter in Book/Report/Conference proceedingChapter

  4. Published
  5. Published

    Gaining mechanistic insight into coproporphyrin I as endogenous biomarker for OATP1B-mediated drug-drug interactions using population pharmacokinetic modelling and simultion

    Barnett, S., Ogungbenro, K., Menochet, K., Shen, H., Humphreys, W. G. & Galetin, A. 2018 In : Clinical Pharmacology & Therapeutics. p. 1-26

    Research output: Contribution to journalArticle

  6. Published

    Gaining mechanistic insight into coproporphyrin I as endogenous biomarker for OATP1B mediated drug-drug interactions using population pharmacokinetic modelling and simulation

    Barnett, S., Ogungbenro, K., Ménochet, K., Shen, H., Lai, Y., Humphreys, W. G. & Galetin, A. 2018 In : Clinical Pharmacology & Therapeutics.

    Research output: Contribution to journalArticle

  7. Published

    Influence of Transporter Polymorphisms on Drug Disposition and Response: A Perspective From the International Transporter Consortium

    Yee, S. W., Brackman, D. J., Ennis, E. A., Sugiyama, Y., Kamdem, L. K., Blanchard, R., Galetin, A., Zhang, L. & Giacomini, K. M. 2018 In : Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticle

  8. Published

    ITC Commentary on Metformin Clinical Drug-Drug Interaction Study Design That Enables an Efficacy- and Safety-Based Dose Adjustment Decision

    Zamek-Gliszczynski, M. J., Chu, X., Cook, J. A., Custodio, J. M., Galetin, A., Giacomini, K. M., Lee, C. A., Paine, M. F., Ray, A. S., Ware, J. A., Wittwer, M. B. & Zhang, L. 2018 In : Clinical Pharmacology and Therapeutics.

    Research output: Contribution to journalArticle

  9. 2017
  10. Published

    Microsomal and cytosolic scaling factors in dog and human kidney cortex and application for in vitro-in vivo extrapolation of renal metabolic clearance

    Scotcher, D., Billington, S., Brown, J., Jones, C. R., Brown, C. D. A., Rostami-Hochaghan, A. & Galetin, A. May 2017 In : Drug Metabolism and Disposition. 45, 5, p. 556-568 13 p.

    Research output: Contribution to journalArticle

  11. Published

    Optimisation of intestinal microsomal preparation in the Rat: A systematic approach to assess the influence of various methodologies on metabolic activity and scaling factors

    Hatley, O., Jones, C. R., Galetin, A. & Rostami-Hochaghan, A. 18 Apr 2017 In : Biopharmaceutics & Drug Disposition. 38, 3, p. 187-208 22 p.

    Research output: Contribution to journalArticle

  12. Published

    Delineating the role of various factors in renal disposition of digoxin through application of physiologically-based kidney model to renal impairment populations

    Scotcher, D., Jones, C., Galetin, A. & Rostami-Hochaghan, A. Mar 2017 In : Journal of Pharmacology and Experimental Therapeutics. 360, 3, p. 484-495 12 p.

    Research output: Contribution to journalArticle

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