Variable Time Normalization Analysis: General Graphical Elucidation of Reaction Orders from Concentration Profiles

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The recent technological evolution of reaction monitoring techniques has not been paralleled by the develop-ment of modern kinetic analyses. The analyses currently used disregard part of the data acquired, thus requiring an increased number of experiments to obtain sufficient kinetic information for a given chemical reaction. Herein, we present a simple graphical analysis method that takes advantage of the data-rich results provided by modern reaction monitoring tools. This analysis uses a variable normalization of the time scale to enable the visual comparison of entire concentration reaction profiles. As a result, the order in each component of the reaction, as well as kobs^, is determined with just a few experiments using a simple and quick mathematical data treatment. This analysis facilitates the rapid extraction of relevant kinetic information and will be a valuable tool for the study of reaction mechanisms.

Bibliographical metadata

Original languageEnglish
Pages (from-to)16084-16087
JournalAngewandte Chemie - International Edition
Early online date25 Nov 2016
Publication statusPublished - 2016

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