Using a novel plug flow reactor for the in situ, simultaneous, monitoring of SAXS and WAXD during crystallisation from solution

Research output: Contribution to journalArticle

  • External authors:
  • Harvey G. Alison
  • John Garside
  • Michael J. Quayle
  • Gordon J T Tiddy
  • David T. Clarke
  • Gareth R. Jones

Abstract

The design and application of a novel plug flow crystalliser is described. Simultaneous collection of SAXS and WAXD during the nucleation and crystal growth of a small organic molecule from solution is reported. Preliminary data imply the separation of a non-diffracting phase prior to the appearance of crystalline solid.

Bibliographical metadata

Original languageEnglish
Pages (from-to)4998-5000
Number of pages2
JournalPhysical Chemistry Chemical Physics
Volume5
Issue number22
DOIs
Publication statusPublished - 15 Nov 2003