Topical treatments for scalp psoriasisCitation formats

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Topical treatments for scalp psoriasis. / Warren, Richard B.; Brown, Benjamin C.; Griffiths, Christopher E M.

In: Drugs, Vol. 68, No. 16, 2008, p. 2293-2302.

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@article{a81e16333d224d0eb12c3dc071f4bf6b,
title = "Topical treatments for scalp psoriasis",
abstract = "Psoriasis is a common, chronic inflammatory skin disease that affects the scalp more commonly than any other site. Scalp psoriasis causes significant psychosocial disability as it is highly visible and can, on occasion, extend onto the face. Furthermore, current treatment regimens are messy, time consuming and, in some instances, ineffective, leading to a high level of non-compliance. The majority of current evidence for topical treatments for this condition comes from open-label, uncontrolled studies. From such studies, there are data to support the use of topical corticosteroids in a number of different formulations and topical vitamin D analogues. However, these studies have not addressed issues such as the need for keratolytics, which may be required to remove adherent scale before a topical corticosteroid or vitamin D analogue may prove efficacious. There is an urgent need for well designed, controlled trials to assess the efficacy of existing and new treatment regimens for scalp psoriasis. The aim of this review is to critically assess the relative effectiveness and tolerability of available topical therapies for this problematic condition and provide recommendations for selection of treatment. {\circledC} 2008 Adis Data Information BV. All rights reserved.",
keywords = "Betamethasone valerate, therapeutic use, Calcipotriol, therapeutic use, Clobetasol, therapeutic use, Dithranol, therapeutic use, Fluocinolone acetonide, therapeutic use, Psoriasis, treatment, Tacalcitol, therapeutic use, Topical",
author = "Warren, {Richard B.} and Brown, {Benjamin C.} and Griffiths, {Christopher E M}",
year = "2008",
doi = "10.2165/0003495-200868160-00003",
language = "English",
volume = "68",
pages = "2293--2302",
journal = "Drugs",
issn = "0012-6667",
publisher = "Adis International Ltd",
number = "16",

}

RIS

TY - JOUR

T1 - Topical treatments for scalp psoriasis

AU - Warren, Richard B.

AU - Brown, Benjamin C.

AU - Griffiths, Christopher E M

PY - 2008

Y1 - 2008

N2 - Psoriasis is a common, chronic inflammatory skin disease that affects the scalp more commonly than any other site. Scalp psoriasis causes significant psychosocial disability as it is highly visible and can, on occasion, extend onto the face. Furthermore, current treatment regimens are messy, time consuming and, in some instances, ineffective, leading to a high level of non-compliance. The majority of current evidence for topical treatments for this condition comes from open-label, uncontrolled studies. From such studies, there are data to support the use of topical corticosteroids in a number of different formulations and topical vitamin D analogues. However, these studies have not addressed issues such as the need for keratolytics, which may be required to remove adherent scale before a topical corticosteroid or vitamin D analogue may prove efficacious. There is an urgent need for well designed, controlled trials to assess the efficacy of existing and new treatment regimens for scalp psoriasis. The aim of this review is to critically assess the relative effectiveness and tolerability of available topical therapies for this problematic condition and provide recommendations for selection of treatment. © 2008 Adis Data Information BV. All rights reserved.

AB - Psoriasis is a common, chronic inflammatory skin disease that affects the scalp more commonly than any other site. Scalp psoriasis causes significant psychosocial disability as it is highly visible and can, on occasion, extend onto the face. Furthermore, current treatment regimens are messy, time consuming and, in some instances, ineffective, leading to a high level of non-compliance. The majority of current evidence for topical treatments for this condition comes from open-label, uncontrolled studies. From such studies, there are data to support the use of topical corticosteroids in a number of different formulations and topical vitamin D analogues. However, these studies have not addressed issues such as the need for keratolytics, which may be required to remove adherent scale before a topical corticosteroid or vitamin D analogue may prove efficacious. There is an urgent need for well designed, controlled trials to assess the efficacy of existing and new treatment regimens for scalp psoriasis. The aim of this review is to critically assess the relative effectiveness and tolerability of available topical therapies for this problematic condition and provide recommendations for selection of treatment. © 2008 Adis Data Information BV. All rights reserved.

KW - Betamethasone valerate, therapeutic use

KW - Calcipotriol, therapeutic use

KW - Clobetasol, therapeutic use

KW - Dithranol, therapeutic use

KW - Fluocinolone acetonide, therapeutic use

KW - Psoriasis, treatment

KW - Tacalcitol, therapeutic use

KW - Topical

U2 - 10.2165/0003495-200868160-00003

DO - 10.2165/0003495-200868160-00003

M3 - Article

VL - 68

SP - 2293

EP - 2302

JO - Drugs

JF - Drugs

SN - 0012-6667

IS - 16

ER -