Time trends in organ position and volume in patients receiving prostate three-dimensional conformal radiotherapy.

Research output: Contribution to journalArticle

  • External authors:
  • James G Mechalakos
  • Gikas S Mageras
  • Michael J Zelefsky
  • Olga Lyass
  • Marcel van Herk
  • Hanne M Kooy
  • Steven A Leibel
  • C Clifton Ling


Using multiple computed tomography (CT) scans, 50 patients undergoing prostate radiotherapy were tested for clinically significant time trends in the target and surrounding critical structures. Significant trends were observed toward increasing bladder volume and increasing bowel-to-planning target volume separation; however, no trends were observed in the prostate, seminal vesicles, or rectum. The subset of patients undergoing hormone therapy was also tested and did not independently exhibit any significant time trends.

Bibliographical metadata

Original languageEnglish
JournalRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Issue number3
Publication statusPublished - Mar 2002