The synthesis of group 10 and 11 metal complexes of 3,6,9-trithia- 1-(2,6)-pyridinacyclodecaphane and their use in A3-coupling reactions

Research output: Contribution to journalArticle

  • External authors:
  • Carlo Brawn
  • David Davies
  • James Raftery
  • Inigo Vitorica-Yrezabal
  • Robin Pritchard
  • Huimin Zhou

Abstract

The reaction between 3,6,9-trithia-1(2,6)-pyridinacyclodecaphane and representative group 10 and 11 metal salts [Cu(NO3)2, NiCl2 or Ag(CF3CO2 )] afforded 1:1 complexes which in the case of Cu(II) and Ag(I) were characterized by single crystal X-ray crystallography. The catalytic activity of these complexes in A3-coupling reactions between aldehydes, terminal alkynes and amines was assessed in both protic (water) and aprotic (toluene) media. These A3-reactions prove to be more efficient, proceed with lower catalyst loadings and with faster reaction rates, when conducted in a focused microwave reactor as compared to the same reactions promoted by standard, thermal, modes of activation

Bibliographical metadata

Original languageEnglish
JournalEuropean Journal of Organic Chemistry
Volume2017
Issue number35
Early online date4 Aug 2017
DOIs
Publication statusPublished - 2017

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