The role of sleep spindles and slow-wave activity in integrating new information in semantic memoryCitation formats

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The role of sleep spindles and slow-wave activity in integrating new information in semantic memory. / Tamminen, Jakke; Lambon Ralph, Matthew A.; Lewis, Penelope A.

In: Journal of Neuroscience, Vol. 33, No. 39, 2013, p. 15376-15381.

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Tamminen, Jakke ; Lambon Ralph, Matthew A. ; Lewis, Penelope A. / The role of sleep spindles and slow-wave activity in integrating new information in semantic memory. In: Journal of Neuroscience. 2013 ; Vol. 33, No. 39. pp. 15376-15381.

Bibtex

@article{740e5946565f45f68cfed1409cbf7238,
title = "The role of sleep spindles and slow-wave activity in integrating new information in semantic memory",
abstract = "Assimilating new information into existing knowledge is a fundamental part of consolidating new memories and allowing them to guide behavior optimally and is vital for conceptual knowledge (semantic memory), which is accrued over many years. Sleep is important for memory consolidation, but its impact upon assimilation of new information into existing semantic knowledge has received minimal examination. Here, we examined the integration process by training human participants on novel words with meanings that fell into densely or sparsely populated areas of semantic memory in two separate sessions. Overnight sleep was polysomnographically monitored after each training session and recall was tested immediately after training, after a night of sleep, and 1 week later. Results showed that participants learned equal numbers of both word types, thus equating amount and difficulty of learning across the conditions. Measures of word recognition speed showed a disadvantage for novel words in dense semantic neighborhoods, presumably due to interference from many semantically related concepts, suggesting that the novel words had been successfully integrated into semantic memory. Most critically, semantic neighborhood density influenced sleep architecture, with participants exhibiting more sleep spindles and slow-wave activity after learning the sparse compared with the dense neighborhood words. These findings provide the first evidence that spindles and slow-wave activity mediate integration of new information into existing semantic networks. {\circledC} 2013 the authors.",
author = "Jakke Tamminen and {Lambon Ralph}, {Matthew A.} and Lewis, {Penelope A.}",
note = "BB/F003048/1, Biotechnology and Biological Sciences Research Council, United Kingdom",
year = "2013",
doi = "10.1523/JNEUROSCI.5093-12.2013",
language = "English",
volume = "33",
pages = "15376--15381",
journal = "The Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "39",

}

RIS

TY - JOUR

T1 - The role of sleep spindles and slow-wave activity in integrating new information in semantic memory

AU - Tamminen, Jakke

AU - Lambon Ralph, Matthew A.

AU - Lewis, Penelope A.

N1 - BB/F003048/1, Biotechnology and Biological Sciences Research Council, United Kingdom

PY - 2013

Y1 - 2013

N2 - Assimilating new information into existing knowledge is a fundamental part of consolidating new memories and allowing them to guide behavior optimally and is vital for conceptual knowledge (semantic memory), which is accrued over many years. Sleep is important for memory consolidation, but its impact upon assimilation of new information into existing semantic knowledge has received minimal examination. Here, we examined the integration process by training human participants on novel words with meanings that fell into densely or sparsely populated areas of semantic memory in two separate sessions. Overnight sleep was polysomnographically monitored after each training session and recall was tested immediately after training, after a night of sleep, and 1 week later. Results showed that participants learned equal numbers of both word types, thus equating amount and difficulty of learning across the conditions. Measures of word recognition speed showed a disadvantage for novel words in dense semantic neighborhoods, presumably due to interference from many semantically related concepts, suggesting that the novel words had been successfully integrated into semantic memory. Most critically, semantic neighborhood density influenced sleep architecture, with participants exhibiting more sleep spindles and slow-wave activity after learning the sparse compared with the dense neighborhood words. These findings provide the first evidence that spindles and slow-wave activity mediate integration of new information into existing semantic networks. © 2013 the authors.

AB - Assimilating new information into existing knowledge is a fundamental part of consolidating new memories and allowing them to guide behavior optimally and is vital for conceptual knowledge (semantic memory), which is accrued over many years. Sleep is important for memory consolidation, but its impact upon assimilation of new information into existing semantic knowledge has received minimal examination. Here, we examined the integration process by training human participants on novel words with meanings that fell into densely or sparsely populated areas of semantic memory in two separate sessions. Overnight sleep was polysomnographically monitored after each training session and recall was tested immediately after training, after a night of sleep, and 1 week later. Results showed that participants learned equal numbers of both word types, thus equating amount and difficulty of learning across the conditions. Measures of word recognition speed showed a disadvantage for novel words in dense semantic neighborhoods, presumably due to interference from many semantically related concepts, suggesting that the novel words had been successfully integrated into semantic memory. Most critically, semantic neighborhood density influenced sleep architecture, with participants exhibiting more sleep spindles and slow-wave activity after learning the sparse compared with the dense neighborhood words. These findings provide the first evidence that spindles and slow-wave activity mediate integration of new information into existing semantic networks. © 2013 the authors.

U2 - 10.1523/JNEUROSCI.5093-12.2013

DO - 10.1523/JNEUROSCI.5093-12.2013

M3 - Article

VL - 33

SP - 15376

EP - 15381

JO - The Journal of Neuroscience

T2 - The Journal of Neuroscience

JF - The Journal of Neuroscience

SN - 0270-6474

IS - 39

ER -