The potential of positron-emission tomography to study anticancer-drug resistance

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Positron-emission tomography (PET) is a powerful tool for imaging and quantifying cellular and molecular processes in humans. It has enormous potential to increase our understanding of the pathophysiology of human tumours and to support the development of anticancer drugs. The ability of PET to image mechanisms of anticancer-drug resistance in vivo should be exploited in proof-of-concept studies at early stages of drug development.

Bibliographical metadata

Original languageEnglish
Pages (from-to)457-469
Number of pages12
JournalNature Reviews Cancer
Issue number6
Publication statusPublished - Jun 2004