The phase behavior and crystallization of 2-chloromandelic acid: The crystal structure of the pure enantiomer and the behavior of its metastable conglomerate

Research output: Contribution to journalArticle

  • External authors:
  • Heike Lorenz
  • Jan Von Langermann
  • Ghazla Sadiq
  • Colin C. Seaon
  • Andreas Seidel-Morgenstern


Crystallization of racemic 2-chloromandelic acid yields a metastable conglomerate in addition to a more stable racemic compound. The crystal structure of the pure enantiomer is reported and the relative stability of the racemic compound and conglomerate was determined at both room temperature and the melting point. Crystallizations from melt and solution are shown to offer potential crystallization pathways to the conglomerate, provided crystallization of the racemic compound can be avoided. © 2011 American Chemical Society.

Bibliographical metadata

Original languageEnglish
Pages (from-to)1549-1556
Number of pages7
JournalCrystal Growth and Design
Issue number5
Publication statusPublished - 4 May 2011

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