Tandem indole C-H alkenylation/arylation for tetra-substituted alkene synthesis

Research output: Contribution to journalArticle

Abstract

Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C-H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene. © 2011 The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)7992-7994
Number of pages2
JournalChemical Communications
Volume47
Issue number28
DOIs
StatePublished - 28 Jul 2011