Tandem indole C-H alkenylation/arylation for tetra-substituted alkene synthesis

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Alkynyl indoles undergo a novel sequence of Pd-catalysed indole C-H activation/alkyne carbopalladation/arylation, with diaryliodonium salts providing the aryl components. An array of functionalised indole alkenes have been prepared in good to excellent yield, with the reaction being selective for the Z-alkene. © 2011 The Royal Society of Chemistry.

Bibliographical metadata

Original languageEnglish
Pages (from-to)7992-7994
Number of pages2
JournalChemical Communications
Issue number28
StatePublished - 28 Jul 2011