Synthesis of 1,3-disubstituted azetidines via a tandem ring-opening ring-closing procedure

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Abstract

The synthesis of N-substituted symmetrical azetidines has been achieved in high yields via the reaction of primary amines undergoing an epoxide ring-opening reaction followed by an in situ ring-closing step.

Bibliographical metadata

Original languageEnglish
Article numberST-2012-D0041-L
Pages (from-to)1511-1515
Number of pages5
JournalSYNLETT
Volume23
Issue number10
DOIs
Publication statusPublished - 30 May 2012

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