Studies on the oxidation and fluorination of α-(phenylsulfanyl)acetamides using (difluoroiodo)toluene

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Abstract

α-(Phenylthio)acetamides are fluorinated in the α-position when treated with 4-(difluoroiodo)toluene (DFIT) in a fluoro-Pummerer reaction. For N-phenylamides, an intramol. Friedel-Crafts reaction may compete and produce heterocycles. [on SciFinder(R)]

Bibliographical metadata

Original languageEnglish
Pages (from-to)4467-4470
Number of pages4
JournalTetrahedron Letters
Volume41
DOIs
StatePublished - 2000