Studies on the additive fluoro-Pummerer reaction of phenylsulfanylated lactams with difluoroiodotoluene

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Two fluorine atoms are effectively introduced to the 3- and 4-positions of sulfur-containing lactams through the action of the hypervalent iodoarene reagent difluoroiodotoluene (DFIT). The reaction proceeds through the intermediacy of the isolable α,β-unsaturated congener followed by an additive-Pummerer process. © 2001 Elsevier Science Ltd. All rights reserved.

Bibliographical metadata

Original languageEnglish
Pages (from-to)8523-8526
Number of pages3
JournalTetrahedron Letters
Issue number48
Publication statusPublished - 26 Nov 2001