Less is known about the structures and processes associated with South-South production networks vis-à-vis those with a South-North orientation. This article explores these differences by taking an inductive approach to
analyse the everyday practices currently employed by Indian pharmaceutical firms to meet production and quality standards, access markets, and to innovate. Extensive primary interview evidence is used to demonstrate how Indian pharmaceutical firms employ divergent business practices according to whether oriented towards Northern or Southern end markets. The findings reveal the significant discontinuities present within the Indian pharmaceutical industry, and demonstrate how a practice oriented approach to the study of GPNs can help to identify some of the micro-social processes through which governance is achieved and transformed over time and divergences in value creation, enhance and capture trajectories between Southern and Northern end markets.