Solution crystallisation via a submerged liquid-liquid phase boundary: Oiling out

Research output: Contribution to journalArticle

  • Authors:
  • P. E. Bonnett
  • K. J. Carpenter
  • S. Dawson
  • R. J. Davey


In many situations the process of crystallisation from solution is known to occur via metastable crystalline states (polymorphs or solvates). Here we present what we believe to be a novel example of small molecule crystallisation in which the initial separation of a solute rich liquid phase precedes the crystallisation event. We believe this occurs because a submerged liquid-liquid phase boundary is accessible within the metastable zone of the crystal nucleation process.

Bibliographical metadata

Original languageEnglish
Pages (from-to)698-699
Number of pages1
JournalChemical Communications
Issue number6
Publication statusPublished - 21 Mar 2003