Solubility study of tobramycin in room temperature ionic liquids: An experimental and computational based study
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Abstract
Herein, we present a computational and experimental study assessing the solubility of tobramycin 1 in a series of hydrophilic room temperature ionic liquids (RTIL). We show that hydrophilic ionic liquids, in particular those containing acetate, [OAc]-, enable significantly enhanced solubilisation of tobramycin in comparison to conventional molecular solvents.
Bibliographical metadata
| Original language | English |
|---|---|
| Pages (from-to) | 107214-107218 |
| Number of pages | 5 |
| Journal | RSC Advances |
| Volume | 6 |
| Issue number | 109 |
| Early online date | 4 Nov 2016 |
| DOIs | |
| Publication status | Published - 2016 |