Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cellsCitation formats

  • External authors:
  • Jennifer Kajahn
  • Erwin Gorjup
  • Stephan Tiede
  • Hagen von Briesen
  • Charli Kruse
  • Sandra Danner

Standard

Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. / Kajahn, Jennifer; Gorjup, Erwin; Tiede, Stephan; von Briesen, Hagen; Paus, Ralf; Kruse, Charli; Danner, Sandra.

In: European journal of cell biology, Vol. 87, No. 1, 15.01.2008, p. 39-46.

Research output: Contribution to journalArticle

Harvard

Kajahn, J, Gorjup, E, Tiede, S, von Briesen, H, Paus, R, Kruse, C & Danner, S 2008, 'Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells', European journal of cell biology, vol. 87, no. 1, pp. 39-46. https://doi.org/10.1016/j.ejcb.2007.07.004

APA

Kajahn, J., Gorjup, E., Tiede, S., von Briesen, H., Paus, R., Kruse, C., & Danner, S. (2008). Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. European journal of cell biology, 87(1), 39-46. https://doi.org/10.1016/j.ejcb.2007.07.004

Vancouver

Kajahn J, Gorjup E, Tiede S, von Briesen H, Paus R, Kruse C et al. Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. European journal of cell biology. 2008 Jan 15;87(1):39-46. https://doi.org/10.1016/j.ejcb.2007.07.004

Author

Kajahn, Jennifer ; Gorjup, Erwin ; Tiede, Stephan ; von Briesen, Hagen ; Paus, Ralf ; Kruse, Charli ; Danner, Sandra. / Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells. In: European journal of cell biology. 2008 ; Vol. 87, No. 1. pp. 39-46.

Bibtex

@article{01c01f9363754fff98edb98424b09d1e,
title = "Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells",
abstract = "Multiple tissue niches in the human body are now recognised to harbour stem cells. Here, we have asked how different adult stem cell populations, isolated from two ontogenetically distinct human organs (skin, pancreas), actually are with respect to a panel of standard markers/characteristics. Here we show that an easily accessible adult human tissue such as skin may serve as a convenient source of adult stem cell-like populations that share markers with stem cells derived from an internal, exocrine organ. Surprisingly, both, human pancreas- and skin-derived stem/progenitor cells demonstrate differentiation patterns across lineage boundaries into cell types of ectoderm (e.g. PGP 9.5+ and GFAP+), mesoderm (e.g. α-SMA+) and entoderm (e.g. amylase+ and albumin+). This intriguing differentiation capability warrants systemic follow-up, since it raises the theoretical possibility that an adult human skin-derived progenitor cell population could be envisioned for possible application in cell replacement therapies. {\circledC} 2007 Elsevier GmbH. All rights reserved.",
keywords = "Pancreas, Plasticity, Skin, Stem cells",
author = "Jennifer Kajahn and Erwin Gorjup and Stephan Tiede and {von Briesen}, Hagen and Ralf Paus and Charli Kruse and Sandra Danner",
year = "2008",
month = "1",
day = "15",
doi = "10.1016/j.ejcb.2007.07.004",
language = "English",
volume = "87",
pages = "39--46",
journal = "European journal of cell biology",
issn = "0171-9335",
publisher = "Urban und Fischer Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Skin-derived human adult stem cells surprisingly share many features with human pancreatic stem cells

AU - Kajahn, Jennifer

AU - Gorjup, Erwin

AU - Tiede, Stephan

AU - von Briesen, Hagen

AU - Paus, Ralf

AU - Kruse, Charli

AU - Danner, Sandra

PY - 2008/1/15

Y1 - 2008/1/15

N2 - Multiple tissue niches in the human body are now recognised to harbour stem cells. Here, we have asked how different adult stem cell populations, isolated from two ontogenetically distinct human organs (skin, pancreas), actually are with respect to a panel of standard markers/characteristics. Here we show that an easily accessible adult human tissue such as skin may serve as a convenient source of adult stem cell-like populations that share markers with stem cells derived from an internal, exocrine organ. Surprisingly, both, human pancreas- and skin-derived stem/progenitor cells demonstrate differentiation patterns across lineage boundaries into cell types of ectoderm (e.g. PGP 9.5+ and GFAP+), mesoderm (e.g. α-SMA+) and entoderm (e.g. amylase+ and albumin+). This intriguing differentiation capability warrants systemic follow-up, since it raises the theoretical possibility that an adult human skin-derived progenitor cell population could be envisioned for possible application in cell replacement therapies. © 2007 Elsevier GmbH. All rights reserved.

AB - Multiple tissue niches in the human body are now recognised to harbour stem cells. Here, we have asked how different adult stem cell populations, isolated from two ontogenetically distinct human organs (skin, pancreas), actually are with respect to a panel of standard markers/characteristics. Here we show that an easily accessible adult human tissue such as skin may serve as a convenient source of adult stem cell-like populations that share markers with stem cells derived from an internal, exocrine organ. Surprisingly, both, human pancreas- and skin-derived stem/progenitor cells demonstrate differentiation patterns across lineage boundaries into cell types of ectoderm (e.g. PGP 9.5+ and GFAP+), mesoderm (e.g. α-SMA+) and entoderm (e.g. amylase+ and albumin+). This intriguing differentiation capability warrants systemic follow-up, since it raises the theoretical possibility that an adult human skin-derived progenitor cell population could be envisioned for possible application in cell replacement therapies. © 2007 Elsevier GmbH. All rights reserved.

KW - Pancreas

KW - Plasticity

KW - Skin

KW - Stem cells

U2 - 10.1016/j.ejcb.2007.07.004

DO - 10.1016/j.ejcb.2007.07.004

M3 - Article

VL - 87

SP - 39

EP - 46

JO - European journal of cell biology

JF - European journal of cell biology

SN - 0171-9335

IS - 1

ER -