Semantic dementia with category specificity: A comparative case-series studyCitation formats

Standard

Semantic dementia with category specificity: A comparative case-series study. / Lambon Ralph, Matthew A.; Patterson, Karalyn; Garrard, Peter; Hodges, John R.

In: Cognitive Neuropsychology, Vol. 20, No. 3-6, 05.2003, p. 307-326.

Research output: Contribution to journalArticle

Harvard

Lambon Ralph, MA, Patterson, K, Garrard, P & Hodges, JR 2003, 'Semantic dementia with category specificity: A comparative case-series study', Cognitive Neuropsychology, vol. 20, no. 3-6, pp. 307-326. https://doi.org/10.1080/02643290244000301

APA

Lambon Ralph, M. A., Patterson, K., Garrard, P., & Hodges, J. R. (2003). Semantic dementia with category specificity: A comparative case-series study. Cognitive Neuropsychology, 20(3-6), 307-326. https://doi.org/10.1080/02643290244000301

Vancouver

Lambon Ralph MA, Patterson K, Garrard P, Hodges JR. Semantic dementia with category specificity: A comparative case-series study. Cognitive Neuropsychology. 2003 May;20(3-6):307-326. https://doi.org/10.1080/02643290244000301

Author

Lambon Ralph, Matthew A. ; Patterson, Karalyn ; Garrard, Peter ; Hodges, John R. / Semantic dementia with category specificity: A comparative case-series study. In: Cognitive Neuropsychology. 2003 ; Vol. 20, No. 3-6. pp. 307-326.

Bibtex

@article{2c44c4f3ee694108a70d53dc7b9d1212,
title = "Semantic dementia with category specificity: A comparative case-series study",
abstract = "Patients with semantic dementia, the temporal variant of frontotemporal dementia, are relevant to both the neuroanatomical and neuropsychological debates in the category-specific literature. These patients present with a selective and progressive semantic deficit consequent on circumscribed atrophy of the inferolateral polar temporal lobes bilaterally, including the inferotemporal gyrus. In this study, a patient KH with a significant advantage for artefacts over living things was compared to five other semantic dementia patients with commensurate levels of semantic impairment. KH demonstrated a consistent category difference in favour of artefacts across all the expressive and receptive semantic tests. This difference was reliable even when familiarity, frequency, and other potential confounding factors were controlled. While KH demonstrated an association between poor knowledge of sensory attributes and a consistently greater impairment on living things than artefacts, the other patients did not. As observed in a number of previous studies, all five of the patients, contrasted to KH, exhibited an advantage for functional/associative over sensory attributes but without demonstrating the category-specific deficit that the sensory-functional theory (and the locus of their atrophy) might predict. The results of this and other studies are discussed in relation to four accounts of category specificity: the sensory-functional theory, domain-specific knowledge systems, intercorrelated features, and individual differences.",
author = "{Lambon Ralph}, {Matthew A.} and Karalyn Patterson and Peter Garrard and Hodges, {John R.}",
note = "700UFCOGNITIVE NEUROPSYCHOL",
year = "2003",
month = "5",
doi = "10.1080/02643290244000301",
language = "English",
volume = "20",
pages = "307--326",
journal = "Cognitive Neuropsychology",
issn = "1464-0627",
publisher = "Psychology Press Ltd",
number = "3-6",

}

RIS

TY - JOUR

T1 - Semantic dementia with category specificity: A comparative case-series study

AU - Lambon Ralph, Matthew A.

AU - Patterson, Karalyn

AU - Garrard, Peter

AU - Hodges, John R.

N1 - 700UFCOGNITIVE NEUROPSYCHOL

PY - 2003/5

Y1 - 2003/5

N2 - Patients with semantic dementia, the temporal variant of frontotemporal dementia, are relevant to both the neuroanatomical and neuropsychological debates in the category-specific literature. These patients present with a selective and progressive semantic deficit consequent on circumscribed atrophy of the inferolateral polar temporal lobes bilaterally, including the inferotemporal gyrus. In this study, a patient KH with a significant advantage for artefacts over living things was compared to five other semantic dementia patients with commensurate levels of semantic impairment. KH demonstrated a consistent category difference in favour of artefacts across all the expressive and receptive semantic tests. This difference was reliable even when familiarity, frequency, and other potential confounding factors were controlled. While KH demonstrated an association between poor knowledge of sensory attributes and a consistently greater impairment on living things than artefacts, the other patients did not. As observed in a number of previous studies, all five of the patients, contrasted to KH, exhibited an advantage for functional/associative over sensory attributes but without demonstrating the category-specific deficit that the sensory-functional theory (and the locus of their atrophy) might predict. The results of this and other studies are discussed in relation to four accounts of category specificity: the sensory-functional theory, domain-specific knowledge systems, intercorrelated features, and individual differences.

AB - Patients with semantic dementia, the temporal variant of frontotemporal dementia, are relevant to both the neuroanatomical and neuropsychological debates in the category-specific literature. These patients present with a selective and progressive semantic deficit consequent on circumscribed atrophy of the inferolateral polar temporal lobes bilaterally, including the inferotemporal gyrus. In this study, a patient KH with a significant advantage for artefacts over living things was compared to five other semantic dementia patients with commensurate levels of semantic impairment. KH demonstrated a consistent category difference in favour of artefacts across all the expressive and receptive semantic tests. This difference was reliable even when familiarity, frequency, and other potential confounding factors were controlled. While KH demonstrated an association between poor knowledge of sensory attributes and a consistently greater impairment on living things than artefacts, the other patients did not. As observed in a number of previous studies, all five of the patients, contrasted to KH, exhibited an advantage for functional/associative over sensory attributes but without demonstrating the category-specific deficit that the sensory-functional theory (and the locus of their atrophy) might predict. The results of this and other studies are discussed in relation to four accounts of category specificity: the sensory-functional theory, domain-specific knowledge systems, intercorrelated features, and individual differences.

U2 - 10.1080/02643290244000301

DO - 10.1080/02643290244000301

M3 - Article

VL - 20

SP - 307

EP - 326

JO - Cognitive Neuropsychology

T2 - Cognitive Neuropsychology

JF - Cognitive Neuropsychology

SN - 1464-0627

IS - 3-6

ER -