Selecting reactions and reactants using a switchable rotaxane organocatalyst with two different active sites

Research output: Contribution to journalArticle

  • External authors:
  • Jack Beswick
  • Victor Blanco
  • Urszula Lewandowska
  • Bartosz Lewandowski
  • Kenji Mishiro

Abstract

The activation mode of a rotaxane-based organocatalyst with both secondary amine and squaramide catalytic units can be switched with acid or base. The macrocycle blocks whichever of the catalytic sites it is positioned over. The switchable rotaxane catalyst generates different products from a mixture of three building blocks according to the location of the macrocyclic ring in the rotaxane.

Bibliographical metadata

Original languageEnglish
Pages (from-to)140-143
Number of pages4
JournalChemical Science
Volume6
Issue number1
DOIs
StatePublished - 2015